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| Cleff,Marlete Brum; Meinerz,Ana Raquel; Xavier,Melissa; Schuch,Luiz Filipe; Meireles,Mário Carlos Araújo; Rodrigues,Maria Regina Alves; Mello,João Roberto Braga de. |
| The aim of this study was to evaluate the in vitro activity of the essential oil extracted from Origanum vulgare against sixteen Candida species isolates. Standard strains tested comprised C. albicans (ATCC strains 44858, 4053, 18804 and 3691), C. parapsilosis (ATCC 22019), C. krusei (ATCC 34135), C. lusitaniae (ATCC 34449) and C. dubliniensis (ATCC MY646). Six Candida albicans isolates from the vaginal mucous membrane of female dogs, one isolate from the cutaneous tegument of a dog and one isolate of a capuchin monkey were tested in parallel. A broth microdilution technique (CLSI) was used, and the inoculum concentration was adjusted to 5 x 10(6) CFU mL-1. The essential oil was obtained by hydrodistillation in a Clevenger apparatus and analyzed by gas... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida; Origanum vulgare; Essential oil; In vitro. |
| Ano: 2010 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822010000100018 |
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| Santin,Rosema; Mattei,Antonella Souza; Waller,Stefanie Bressan; Madrid,Isabel Martins; Cleff,Marlete Brum; Xavier,Melissa Orzechowski; Nobre,Márcia de Oliveira; Nascente,Patrícia da Silva; Mello,João Roberto Braga de; Meireles,Mário Carlos Araújo. |
| The oral microbiota of humans and animals is made up of a wide variety of yeasts and bacteria, but microbiota of dogs is not totally described. Although such identification is an important step to establish the etiopathogenesis and adequate therapy for the periodontal disease The aim of this study was to evaluate and correlate oral alterations with the presence of yeasts in oral cavity of female dogs. After clinical evaluation samples from healthy and from dogs with oral diseases were obtained from three different oral sites by swabs, curettes, millimeter periodontal probes and HA membrane tip in cellulose ester. Yeast identification was performed through macroscopic and microscopic colony features and biochemical tests. Dental calculus was the most... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oral microbiota; Yeasts; M. pachydermatis; Candida spp.; Halitosis. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000100020 |
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| Cleff,Marlete Brum; Lima,Alzira Pacheco de; Faria,Renata Osório de; Meinerz,Ana Raquel Mano; Antunes,Tatiana de Ávila; Araújo,Flávia Biasoli de; Nascente,Patrícia da Silva; Nobre,Márcia de Oliveira; Meireles,Mário Carlos Araújo. |
| Yeasts are commensal organisms found in the skin, genital and gastrointestinal tracts, and other mucosa in mammalians. Candida spp has been frequently isolated from domestic and sylvan animals. Yeast isolation from vaginal mucus is frequent in women, especially of Candida genus. In canine females, however, studies about vaginal fungal microbiota are rare and the connection with estrous cycle is unknown. The purpose of this study was to isolate yeast 5 of Candida genus from healthy canine females and identify the isolated species, establishing their connection with estrous cycle phases. Two hundred twenty-four samples taken from vaginal mucus of 14 canine females were analyzed in this study. Candida spp was observed in 83 (37%) from these samples; nine... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Candida spp; Canine females; Estrous cycle. |
| Ano: 2005 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822005000200018 |
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| Waller,Stefanie Bressan; Madrid,Isabel Martins; Ferraz,Vanny; Picoli,Tony; Cleff,Marlete Brum; de Faria,Renata Osório; Meireles,Mário Carlos Araújo; de Mello,João Roberto Braga. |
| Abstract The study aimed to evaluate the anti-Sporothrix sp. activity of the essential oil of Origanum majorana Linn. (marjoram), its chemical analysis, and its cytotoxic activity. A total of 18 fungal isolates of Sporothrix brasiliensis (n: 17) from humans, dogs and cats, and a standard strain of Sporothrix schenckii (n: 1) were tested using the broth microdilution technique (Clinical and Laboratory Standard Institute - CLSI M27-A3) and the results were expressed in minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC). The MIC50 and MIC90 of itraconazole against S. brasiliensis were 2 µg/mL and 8 µg/mL, respectively, and the MFC50 and MFC90 were 2 µg/mL and >16 µg/mL, respectively, with three S. brasiliensis isolates... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sporotrichosis; Sporothrix schenckii complex; Antifungal resistance; Marjoram; Lamiaceae. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822016000400896 |
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| Waller,Stefanie Bressan; Nakasu,Ceres; Silva,Anna Luiza; Faria,Renata Osório de; Fernandes,João Paulo dos Santos; Cleff,Marlete Brum. |
| From drug repurposing studies, this work aimed to evaluate the activity of different pyrazinoic acid (POA) derivatives against Sporothrix brasiliensis. The POA esters were prepared and characterized as previously reported by classical esterification reactions, with good to excellent yields. Sporothrix brasiliensis isolates from cats (n=6) and standard strains of S. brasiliensis and S. schenckii were used to assess the antifungal activity of the POA derivatives through broth microdilution assay (CLSI M38-A2). Among the tested compounds, molecules 3 and 4 showed fungistatic and fungicidal activities against all Sporothrix spp. strains, and the obtained MIC and MFC values ranged from 2.12 to 4.24 mg/mL and from 1.29 to 5.15 mg/mL, respectively. Compound 2 and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sporotrichosis; Sporothrix schenckii complex; Itraconazole; Antifungal resistance; Prodrugs; Pyrazinoic acid derivatives. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000400630 |
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| Waller,Stefanie Bressan; Madrid,Isabel Martins; Faria,Renata Osório de; Cleff,Marlete Brum; Mello,João Roberto Braga de; Meireles,Mário Carlos Araújo. |
| ABSTRACT Cases of sporotrichosis in humans and animals without satisfactory clinical response have increased, a warning sign of strains resistant to conventional antifungal agents. The urgent search for alternative therapies was an incentive for research on medicinal plants with anti-Sporothrix spp. properties. A bibliographic survey was performed based on scientific papers about in vitro and in vivo antifungal activity of essential oils and extracts of plants in differents solvents against the fungal of the Sporothrix schenckii complex. The study methodology consisted of a literature review in Google Scholar, Science Direct, Pubmed, Bireme and Springer link with papers from 1986 to 2015. We found 141 species of plants that were investigated, of which 100... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Sporothrix schenckii complex; Antifungals; Combretaceae/pharmacognosy; Asteraceae/pharmacognosy; Lamiaceae/pharmacognosy; Medicinal plants/antifungal activity. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000200221 |
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