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| Cordeiro,L.M.S.; Rabelo,P.C.R.; Moraes,M.M.; Teixeira-Coelho,F.; Coimbra,C.C.; Wanner,S.P.; Soares,D.D.. |
| Brain serotonin and dopamine are neurotransmitters related to fatigue, a feeling that leads to reduced intensity or interruption of physical exercises, thereby regulating performance. The present review aims to present advances on the understanding of fatigue, which has recently been proposed as a defense mechanism instead of a “physiological failure” in the context of prolonged (aerobic) exercises. We also present recent advances on the association between serotonin, dopamine and fatigue. Experiments with rodents, which allow direct manipulation of brain serotonin and dopamine during exercise, clearly indicate that increased serotoninergic activity reduces performance, while increased dopaminergic activity is associated with increased performance.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brain; Lethargy; Monoamines; Performance; Physical activity; Reward. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017001200301 |
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