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Oxidative stress in sepsis. Possible production of free radicals through an erythrocyte-mediated positive feedback mechanism BJID
Oliveira,Yanaihara Pinchemel Amorim de; Pontes-de-Carvalho,Lain Carlos; Couto,Ricardo David; Noronha-Dutra,Alberto Augusto.
Abstract Background: Sepsis is an illness with a high morbidity for which no effective treatment exists. Its treatment has a high cost because it usually requires an intensive care unit and expensive antibiotics. The present study focus in the production of reactive oxygen species in the early stages of sepsis. This study aimed at investigating the production of reactive oxygen specie during the inflammatory response in patients with sepsis. Methods: Reactive oxygen specie production and insoluble myeloperoxidase obtained from fresh whole blood were measured by photon counting chemiluminescence in the blood of 18 septic patients and 12 healthy individuals. Modified red blood cells were evaluated by staining of blood smears. The production of reactive...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Sepsis; Oxidative stress; Inflammation; Modified erythrocytes.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000100019
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Essential oil of Lippia alba in the transport of Nile tilapia Ciência Rural
Hohlenwerger,Janis Cumming; Baldisserotto,Bernardo; Couto,Ricardo David; Heinzmann,Berta Maria; Silva,Daniela Thomas da; Caron,Braulio Otomar; Schmidt,Denise; Copatti,Carlos Eduardo.
ABSTRACT: This study aimed to examine the action of the essential oil of Lippia alba (EOLA) in the stress response for transport of Nile tilapia Oreochromis niloticus . The fish were transported into three treatments (in triplicate): control, 10 and 20 µL L-1 EOLA, with loading density of 15 fish/plastic bags for 8h. Plasma glucose levels were significantly decreased in fish exposed to 20µL L-1 EOLA in comparison with the control group and fish exposed to 10µL L-1 EOLA, but the plasma cortisol, lactate and paraoxonase levels were similar. Un-ionized ammonia and ventilatory rate demonstrated a significant reduction in the treatments with the use of EOLA. In conclusion the use of 20µL L-1 EOLA is indicated for Nile tilapia transport.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Oreochromis niloticus; Stress; Glucose; Cortisol; Ventilatory rate.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000300403
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