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	Provedor de dados BJMBR (1) Autor Cui,S.L. (1) Ma,Z.G. (1) Xia,H.Q. (1) Yu,J. (1) Palavra-chave Inflammation (1) Oxidative stress (1) PI3K/Akt pathway (1) Renal ischemic reperfusion (1) Salvianolic acid B (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2017 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Attenuation of renal ischemic reperfusion injury by salvianolic acid B via suppressing oxidative stress and inflammation through PI3K/Akt signaling pathway BJMBR Ma,Z.G.; Xia,H.Q.; Cui,S.L.; Yu,J.. Salvianolic acid B (SAB) is one the major phytocomponents of Radix Salvia miltiorrhiza and exhibit numerous health promoting properties. The objective of the current study was to examine whether SAB exerts a renoprotective effect by attenuating oxidative stress and inflammatory response through activating phosphatidylinositol 3-kinase/serine-threonine kinase B (PI3K/Akt) signaling pathway in a renal ischemic reperfusion rat model. Forty Sprague-Dawley male rats (250–300 g) were obtained and split into four groups with ten rats in each group. The right kidney of all rats was removed (nephrectomy). The rats of the Control group received only saline (occlusion) and served as a sham control group, whereas rats subjected to ischemic reperfusion (IR) insult by... Tipo: Info:eu-repo/semantics/article Palavras-chave: Renal ischemic reperfusion; Salvianolic acid B; Oxidative stress; Inflammation; PI3K/Akt pathway. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000600607 Registros recuperados: 1 Primeira ... 1 ... Última

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