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Bocco,B.M.; Fernandes,G.W.; Lorena,F.B.; Cysneiros,R.M.; Christoffolete,M.A.; Grecco,S.S.; Lancellotti,C.L.; Romoff,P.; Lago,J.H.G.; Bianco,A.C.; Ribeiro,M.O.. |
Fractionation of the EtOH extract from aerial parts of Baccharis uncinella C. DC. (Asteraceae) led to isolation of caffeic and ferulic acids, which were identified from spectroscopic and spectrometric evidence. These compounds exhibit antioxidant and anti-inflammatory properties and have been shown to be effective in the prevention/treatment of metabolic syndrome. This study investigated whether the combined treatment of caffeic and ferulic acids exhibits a more significant beneficial effect in a mouse model with metabolic syndrome. The combination treatment with caffeic and ferulic acids was tested for 60 days in C57 mice kept on a high-fat (40%) diet. The data obtained indicated that treatment with caffeic and ferulic acids prevented gain in body weight... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Obesity; Caffeic acid; Ferulic acid; Metabolic syndrome. |
Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000300604 |
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