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García-Coronado,Heriberto; Troncoso-Rojas,Rosalba; Tiznado-Hernández,Martín Ernesto; de la Cruz Otero,María del Carmen; Díaz-Camacho,Sylvia Páz; Báez-Flores,María Elena. |
Background Isothiocyanates (ITCs) are natural products obtained from plants of the Brassicas family. They represent an environmentally friendly alternative for the control of phytopathogenic fungi. However, as it has been observed with synthetic fungicides, the possibility of inducing ITC-resistant strains is a major concern. It is, therefore, essential to understanding the molecular mechanisms of fungal resistance to ITCs. We analyzed a subtractive library containing 180 clones of an Alternaria alternata strain resistant to 2-propenyl ITC (2-pITC). After their sequencing, 141 expressed sequence tags (ESTs) were identified using the BlastX algorithm. The sequence assembly was carried out using CAP3 software; the functional annotation and metabolic pathways... |
Tipo: Journal article |
Palavras-chave: Blast2GO analysis; Fungal drug tolerance; Isothiocyanates; Natural fungicides. |
Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-34582015000400011 |
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Díaz-Carrillo,José Tomás; Díaz-Camacho,Sylvia Páz; Delgado-Vargas,Francisco; Rivero,Ignacio Alfredo; López-Angulo,Gabriela; Sarmiento-Sánchez,Juan Ignacio; Montes-Avila,Julio. |
The hymenolepiosis by Hymenolepis nana is a major public health problem in developing countries, and the commercial drugs against this parasitosis are not enough effective. The combination of antiparasitic and antioxidant agents has improved the treatment of some parasitoses. Thus, the development of new cestocidal and antioxidant agents to treat the hymenolepiosis cases is important. In the present study, four hydroxy- and four dihydroxy-chalcones were synthesized using the catalyst boron trifluoride diethyl etherate (BF3•OEt2). The antioxidant activity and antiparasitic against H. nana of chalcones were tested, as well as the toxicity by the brine shrimp lethality bioassay and the method of Lorke. The antioxidant activity was measured by three radical... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hymenolepis nana; Chalcone/synthesis/antiparasitic/antioxidant activity.. |
Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000300610 |
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