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| SCHAFFER,THAYS K.; WOHLENBERG,MARIANE F.; MEDEIROS,NIARA; MARTINS,JÉSSICA B.; AGOSTINI,FABIANA; FUNCHAL,CLÁUDIA; DANI,CAROLINE. |
| The aim of this study was to evaluate the hepatoprotection of organic and conventional grapevine leaves extract (Vitis labrusca). The total polyphenol content and the isolate polyphenols by HPLC were evaluate. The animals received intraperitoneal injections of saline or extracts (conventional or organic - 30 mg/kg) for 14 days. On day 15, the rats received carbon tetrachloride (CCl4) or mineral oil (i.p.). After 4h, the animals were euthanized. The analysis of the liver enzymes activity (AST, ALT, GGT) was performed using serum, obtained by blood and the levels of lipid peroxidation (TBARS), protein oxidation (carbonyl), and the activity of antioxidant enzymes superoxide dismutase and catalase were analyzed in the liver. The results showed that the organic... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Oxidative stress; Carbon tetrachloride; Hepatoprotection; Grapes; Phenolic compounds. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000100187 |
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| DANI,CAROLINE; ANDREAZZA,ANA CRISTINA; GONÇALVES,CARLOS ALBERTO; KAPIZINSKI,FLÁVIO; HENRIQUES,JOÃO A. P.; SALVADOR,MIRIAN. |
| ABSTRACT Several studies have shown that a high consumption of vegetables and fruits is consistently associated with a low risk of oxidative stress-induced diseases, which includes some degenerative diseases such as amyotrophic lateral sclerosis, Alzheimer and Parkinson. Therefore, the objective of this study is to verify the effects of conventional and organic grape juice in the modulation of the neurotrophic factor (BDNF) and astrocytic markers protein (S100B) in hippocampus and frontal cortex of Wistar rats. In this study, 24 male Wistar rats were divided into three groups. To the first one, it was given organic purple grape juice; to the second, conventional grape juice, while the last one received only saline. After 30 days, all rats were sacrificed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brain; Grape juice; Neuroprotection; Polyphenol.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652017000100155 |
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| BOKOWSKI,LIANE V.V.; SOBRINHO,ROBERTO B.; ARMIJO,CRISTIÁN J.V.; DANI,CAROLINE; HENRIQUES,JOÃO A.P.; FUNCHAL,CLÁUDIA. |
| ABSTRACT Vitis labrusca L. is the main species used for wine and juice production in Brazil. The grapevine leaves can be used both as functional foods and as cheapest sources for the extraction of phenolic compounds. Besides the antioxidant activity, grapevine leaves exhibited significant anti-inflammatory activity. Therefore, the aim of this study was to develop and validate an analytical methodology to determine the metals selenium (96Se), chromium (53Cr), nickel (62Ni), cadmium (111Cd) and lead (206Pb) in 30 samples of grapevine leaf extracts (Vitis labrusca, Bordo cultivar) using inductively coupled plasma mass spectrometry (ICP-MS). To obtain the grapevine leaf extracts the samples were milled, weighed and digested in microwave oven with nitric acid.... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: ICP-MS; Metals; Method validation; Vitis labrusca L. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000602247 |
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