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	Provedor de dados BJMBR (2) Autor Da Poian,A.T. (2) Carneiro,F.A. (1) Conceição,T.M. (1) Montero-Lomelí,M. (1) Ramírez,J. (1) Santoro,A.B.M. (1) Stauffer,F. (1) Villas-Bôas,C.S.A. (1) Mais... Palavra-chave Dengue virus (1) Flavivirus (1) Fusion proteins (1) G protein (1) Glycoprotein (1) Membrane fusion (1) Protein synthesis (1) Rhabdovirus (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2009 (1) 2005 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Viral membrane fusion: is glycoprotein G of rhabdoviruses a representative of a new class of viral fusion proteins? BJMBR Da Poian,A.T.; Carneiro,F.A.; Stauffer,F.. Enveloped viruses always gain entry into the cytoplasm by fusion of their lipid envelope with a cell membrane. Some enveloped viruses fuse directly with the host cell plasma membrane after virus binding to the cell receptor. Other enveloped viruses enter the cells by the endocytic pathway, and fusion depends on the acidification of the endosomal compartment. In both cases, virus-induced membrane fusion is triggered by conformational changes in viral envelope glycoproteins. Two different classes of viral fusion proteins have been described on the basis of their molecular architecture. Several structural data permitted the elucidation of the mechanisms of membrane fusion mediated by class I and class II fusion proteins. In this article, we review a number of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Membrane fusion; Fusion proteins; Rhabdovirus; G protein; Glycoprotein. Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2005000600002 Dengue virus-induced regulation of the host cell translational machinery BJMBR Villas-Bôas,C.S.A.; Conceição,T.M.; Ramírez,J.; Santoro,A.B.M.; Da Poian,A.T.; Montero-Lomelí,M.. Dengue virus (DV)-induced changes in the host cell protein synthesis machinery are not well understood. We investigated the transcriptional changes related to initiation of protein synthesis. The human hepatoma cell line, HepG2, was infected with DV serotype 2 for 1 h at a multiplicity of infection of one. RNA was extracted after 6, 24 and 48 h. Microarray results showed that 36.5% of the translation factors related to initiation of protein synthesis had significant differential expression (Z-score ≥ ±2.0). Confirmation was obtained by quantitative real-time reverse transcription-PCR. Of the genes involved in the activation of mRNA for cap-dependent translation (eIF4 factors), eIF4A, eIF4G1 and eIF4B were up-regulated while the negative regulator of... Tipo: Info:eu-repo/semantics/article Palavras-chave: Dengue virus; Flavivirus; Protein synthesis. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001100004 Registros recuperados: 2 Primeira ... 1 ... Última

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