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	Provedor de dados Genet. Mol. Biol. (1) Autor Dalberto,Tiago Pires (1) Nardi,Nance Beyer (1) Silva,Flávia Helena da (1) Palavra-chave Gene therapy (1) HIV (1) Lentivirus (1) MLV (1) Retrovirus (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2006 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Beyond retrovirus infection: HIV meets gene therapy Genet. Mol. Biol. Silva,Flávia Helena da; Dalberto,Tiago Pires; Nardi,Nance Beyer. The human immunodeficiency virus (HIV) is classified as a retrovirus because of its RNA genome and the fact that it requires reverse transcriptase to convert it into DNA. This virus belongs to the lentivirinae subfamily and is able to infect quiescent cells but is better known for its association with acquired immunodeficiency syndrome (AIDS) and can be described as one of the most effective vectors for gene transfer. Biosafety concerns are present whenever viral vectors are employed but are particularly pertinent to the development of HIV-based vectors. Insertional mutagenesis and the production of new replication-competent viruses (RCV) have been pointed to as major problems, but experimental data have shown that safe protocols can be developed for their... Tipo: Info:eu-repo/semantics/article Palavras-chave: HIV; MLV; Retrovirus; Lentivirus; Gene therapy. Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572006000200027 Registros recuperados: 1 Primeira ... 1 ... Última

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