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Restless leg syndrome, sleep quality and fatigue in multiple sclerosis patients BJMBR
Moreira,N.C.V.; Damasceno,R.S.; Medeiros,C.A.M.; de Bruin,P.F.C.; Teixeira,C.A.C.; Horta,W.G.; de Bruin,V.M.S..
We have tested the hypothesis that restless leg syndrome (RLS) is related to quality of sleep, fatigue and clinical disability in multiple sclerosis (MS). The diagnosis of RLS used the four minimum criteria defined by the International Restless Legs Syndrome Study Group. Fatigue was assessed by the Fatigue Severity Scale (FSS >27), quality of sleep by the Pittsburgh Sleep Quality Index (PSQI >6), excessive daytime sleepiness by the Epworth Sleepiness Scale (ESS >10) and clinical disability by the Expanded Disability Status Scale (EDSS). Forty-four patients (32 women) aged 14 to 64 years (43 ± 14) with disease from 0.4 to 23 years (6.7 ± 5.9) were evaluated. Thirty-five were classified as relapsing-remitting, 5 as primary progressive and 4 as...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Restless leg syndrome; Multiple sclerosis; Sleep; Fatigue; Pittsburgh Sleep Quality Index.
Ano: 2008 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001000017
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Central chemoreceptors and neural mechanisms of cardiorespiratory control BJMBR
Takakura,A.C.; Damasceno,R.S.; Falquetto,B.; Totola,L.T.; Sobrinho,C.R.; Ragioto,D.T.; Zolezi,F.P..
The arterial partial pressure (P CO2) of carbon dioxide is virtually constant because of the close match between the metabolic production of this gas and its excretion via breathing. Blood gas homeostasis does not rely solely on changes in lung ventilation, but also to a considerable extent on circulatory adjustments that regulate the transport of CO2 from its sites of production to the lungs. The neural mechanisms that coordinate circulatory and ventilatory changes to achieve blood gas homeostasis are the subject of this review. Emphasis will be placed on the control of sympathetic outflow by central chemoreceptors. High levels of CO2 exert an excitatory effect on sympathetic outflow that is mediated by specialized chemoreceptors such as the neurons...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Chemoreflex; Cardiorespiratory responses; Ventrolateral medulla; Sympathetic nerve activity; Phrenic nerve activity.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900009
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