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Episodes of water deprivation enhance daily hypertonic NaCl intake in rats BJMBR
Pereira,D.T.B.; David,R.B.; Menani,J.V.; De Luca Jr.,L.A..
Water and 1.8% NaCl intake was recorded daily in adult male rats (N = 6) submitted to four water deprivations plus four sodium appetite tests, each at the end of each 7-day interval, or in controls (non-deprived, N = 6). Water deprivation was achieved by removing water and 1.8% NaCl for 24 h. Water was then offered for 2 h. At the end of this period, 1.8% NaCl was also offered in addition to water (sodium appetite test). Average daily 1.8% NaCl intake was enhanced from 5.2 ± 1.0 to 15.7 ± 2.5 ml from the first to the fifth week in the experimental group and was unchanged in the control group. Daily water intake was not altered in either group. Thus, repeated episodes of water deprivation enhance daily NaCl intake.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Thirst; Salt appetite; Dehydration; Natriuresis.
Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000400009
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Water deprivation and the double- depletion hypothesis: common neural mechanisms underlie thirst and salt appetite BJMBR
De Luca,L.A. Jr; Vendramini,R.C.; Pereira,D.T.B.; Colombari,D.A.S.; David,R.B.; Paula,P.M.; Menani,J.V..
Water deprivation-induced thirst is explained by the double-depletion hypothesis, which predicts that dehydration of the two major body fluid compartments, the extracellular and intracellular compartments, activates signals that combine centrally to induce water intake. However, sodium appetite is also elicited by water deprivation. In this brief review, we stress the importance of the water-depletion and partial extracellular fluid-repletion protocol which permits the distinction between sodium appetite and thirst. Consistent enhancement or a de novo production of sodium intake induced by deactivation of inhibitory nuclei (e.g., lateral parabrachial nucleus) or hormones (oxytocin, atrial natriuretic peptide), in water-deprived, extracellular-dehydrated...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Water deprivation; Dehydration; Mineral preference; Sodium appetite; Cravings.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000500015
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