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	Provedor de dados BJID (2) Autor De Gaspari,Elizabeth N. (2) Belo,Elza F.T. (1) Coutinho,Ligia M.C.C. (1) Ferraz,Aline S. (1) Zollinger,Wendell D. (1) Palavra-chave Monoclonal antibodies (2) Neisseria meningitidis (2) Brazilian meningococcus strains (1) Flow cytometry (1) Outer membrane protein (1) Serotyping (1) Subtyping (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2004 (1) 2001 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Production of monoclonal antibody to subtype 9 of Neisseria meningitidis and the distribution of this subtype in Brazil BJID Belo,Elza F.T.; Coutinho,Ligia M.C.C.; Ferraz,Aline S.; De Gaspari,Elizabeth N.. A new monoclonal antibody (5F81A4P1.9), which is specific for subtype 9 antigen of meningococci, was studied. The antibodies were raised against a previously non-typable (NT) serogroup B strain from Brazilian patients and were found to react with the subtype antigen of prototype reference strains for subtype 9 (M982), as well as with those of homologous strains. The subtype 9 epitope was found in 6.8% of serogroup B strains among 602 strains of Neisseria meningitidis case isolates, including representative isolates from Brazilian states. Subtype P1.9 was predominantly related to serogroup B in Brazil among the isolates collected during the N. meningitidis epidemic in 1992. No significant differences were observed in the occurrence of subtype P1.9 among... Tipo: Info:eu-repo/semantics/article Palavras-chave: Neisseria meningitidis; Monoclonal antibodies; Brazilian meningococcus strains; Serotyping; Subtyping. Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000600004 Expression of class 5 antigens by meningococcal strains obtained from patients in Brazil and evaluation of two new monoclonal antibodies BJID De Gaspari,Elizabeth N.; Zollinger,Wendell D.. Determining the profile of antigen expression among meningococci is important for epidemiologic surveillance and vaccine development. To this end, two new mouse monoclonal antibodies (MAbs) have been derived against Neisseria meningitidis proteins (class 5). The MAbs were reactive against outer membrane antigens and were bactericidal. Selected anti-class 5 MAbs [(5.1)-3E6-2; (5.3)-3BH4-C7; (5.4)-1BG11-C7; (5.5)-3DH-F5G9 also 5F1F4-T3(5.c)], and the two new monoclonal antibodies C14F10Br2 (5.8) and 7F11B5Br3 (5.9), were then tested against different meningococcal strains, (63 strains of serogroup A, 60 strains of serogroup C (from 1972 to 1974); and 136 strains of serogroup B (from 1992) meningococci). Our results demonstrated that the expression of class 5... Tipo: Info:eu-repo/semantics/article Palavras-chave: Neisseria meningitidis; Monoclonal antibodies; Outer membrane protein; Flow cytometry. Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000300007 Registros recuperados: 2 Primeira ... 1 ... Última

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