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Association of IGF-I gene polymorphisms with milk yield and body size in Chinese dairy goats Genet. Mol. Biol.
Deng,Chanjuan; Ma,Rongnuan; Yue,Xiangpeng; Lan,Xianyong; Chen,Hong; Lei,Chuzhao.
The association of IGF-I gene polymorphisms with certain traits in 708 individuals of two Chinese dairy-goat breeds (Guanzhong and Xinong Saanen) was investigated. Polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) and DNA sequencing methods were employed in screening for genetic variation. Two novel mutations were detected in the 5'-flanking region and in intron 4 of IGF-I gene, viz., g.1617 G > A and g.5752 G > C (accession D26119.2), respectively. The associations of the g.1617 G > A mutation with milk yield and the body size were not significant (p > 0.05). However, in the case of g.5752 G > C, Xinong Saanen dairy goats with the CG genotype presented longer bodies (p < 0.05). Chest circumference (p < 0.05)...
Tipo: Info:eu-repo/semantics/article Palavras-chave: IGF-I gene; Dairy goat; Milk yield; PCR- SSCP.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572010000200012
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