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Kang,Jing; Liu,Jing; Ding,Haibo; Li,Xiaolin; Wang,Qi; Guo,Xiaolin; Geng,Wenqing; Shang,Hong. |
Objectives: Men who have sex with men are at risk of tenofovir nephrotoxicity due to its wide use in both treatment and prophylaxis for human immunodeficiency virus infection, but little is known about the urinary biomarkers of early renal dysfunction in this population. This study aims to identify useful biomarkers of early renal dysfunction among human immunodeficiency virus-infected men who have sex with men exposed to tenofovir.Methods: In a cross-sectional study urinary alpha1-microglobulin, beta2-microglobulin, N-acetyl-B-n-glucosaminidase and albumin were measured and expressed as the ratio-to-creatinine in 239 human immunodeficiency virus-infected men who have sex with men who were treatment naïve or receiving antiretroviral therapy with... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Alpha1-microglobulin; Beta2-microglobulin; Tenofovir; Human immunodeficiency virus. |
Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702015000400410 |
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