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	Provedor de dados 74 (1) Autor Ding,Jiayi (1) Liang,Qiaoyi (1) Zheng,Shu (1) Palavra-chave Endogenous retrovirus (1) Noncoding RNA (1) Quantitative real-time PCR (1) RT-PCR (1) Transcription (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2009 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Identification and detection of a novel human endogenous retrovirus-related gene, and structural characterization of its related elements 74 Liang,Qiaoyi; Ding,Jiayi; Zheng,Shu. Up-regulation of human endogenous retroviruses (HERVs) is associated with many diseases, including cancer. In this study, an H family HERV (HERV-H)-related gene was identified and characterized. Its spliced transcript lacks protein-coding capacity and may belong to the emerging class of noncoding RNAs (ncRNAs). The 1.3-kb RNA consisting of four exons is transcribed from an Alu element upstream of a 5.0-kb structurally incomplete HERV-H element. RT-PCR and quantitative RT-PCR results indicated that expression of this HERV-related transcript was negatively associated with colon, stomach, and kidney cancers. Its expression was induced upon treatment with DNA methylation and histone deacetylation inhibitors. A BLAT search using long terminal repeats (LTRs)... Tipo: Info:eu-repo/semantics/article Palavras-chave: Endogenous retrovirus; Noncoding RNA; RT-PCR; Quantitative real-time PCR; Transcription. Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572009000400005 Registros recuperados: 1 Primeira ... 1 ... Última

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