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Low seroprevalence of Zika virus in Cameroonian blood donors BJID
Gake,Bouba; Vernet,Marie A.; Leparc-Goffart,Isabelle; Drexler,Jan Felix; Gould,Ernest A.; Gallian,Pierre; Lamballerie,Xavier de.
Abstract A Zika virus seroepidemiology study was performed in 1084 blood donors collected from August to October 2015 in six sites of Cameroon representing a large panel of eco-environments. Samples were tested using an anti-NS1 IgG ELISA detection kit and positives were further confirmed by seroneutralization. The observed global seroprevalence was low (around 5%, peaking at 10% and 7.7% in Douala and Bertoua, respectively) with risk factors associated with seropositivity pointing to the existence of a local (peri-)sylvatic cycle of transmission. These results call attention to the potential introduction and subsequent spread in African urban areas of Asian genotype Zika virus currently circulating in the Americas and adapted to transmission by...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Zika virus; Seroprevalence; Africa.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000400481
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Theories about evolutionary origins of human hepatitis B virus in primates and humans BJID
Souza,Breno Frederico de Carvalho Dominguez; Drexler,Jan Felix; Lima,Renato Santos de; Rosário,Mila de Oliveira Hughes Veiga do; Netto,Eduardo Martins.
Introduction:The human hepatitis B virus causes acute and chronic hepatitis and is considered one of the most serious human health issues by the World Health Organization, causing thousands of deaths per year. There are similar viruses belonging to the Hepadnaviridae family that infect non-human primates and other mammals as well as some birds. The majority of non-human primate virus isolates were phylogenetically close to the human hepatitis B virus, but like the human genotypes, the origins of these viruses remain controversial. However, there is a possibility that human hepatitis B virus originated in primates. Knowing whether these viruses might be common to humans and primates is crucial in order to reduce the risk to humans.Objective:To review the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Hepatitis B virus; Hepadnaviridae; Non-human primates; Evolutionary origins.
Ano: 2014 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702014000500535
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