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| Barros,Rosana Rocha; Kegele,Fabíola Cristina Oliveira; Paula,Geraldo Renato de; Brito,Monique Araújo de; Duarte,Rafael Silva. |
| Three isolates of Streptococcus agalactiae, recovered from residents of the metropolitan area of Rio de Janeiro with significant bacteriuria, were found to be resistant to levofloxacin. Determination of the minimal inhibitory concentration (MIC) confirmed one isolate as intermediate and two as resistant to levofloxacin. No reduction in levofloxacin MIC was observed with reserpine, indicating that resistance was not caused by an efflux mechanism. Typical point mutations were observed in the quinolone resistance determinant region of gyrA and parC. Other point mutations in parC generated novel altered codons: Ser80→Pro in the intermediate resistance isolate, and Gly128→Asp in a resistant isolate. Through molecular modeling, it was possible to observe that... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Fluoroquinolone resistance; Bacteriuria; Genetic diversity; Streptococcus agalactiae. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000500013 |
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| Monego,Fernanda; Duarte,Rafael Silva; Nakatani,Sueli Massumi; Araújo,Wildo Navegantes; Riediger,Irina Nastassja; Brockelt,Sonia; Souza,Verena; Cataldo,Jamyra Iglesias; Dias,Rubens Clayton da Silva; Biondo,Alexander Welker. |
| OBJECTIVE: One hundred thirty-one cases of postsurgical infections were reported in Southern Region of Brazil between August 2007 and January 2008. Thirty-nine (29.8%) cases were studied; this report describes epidemiological findings, species identification, antimicrobial susceptibility and clonal diversity of rapidly growing mycobacteria isolated in this outbreak. METHODS: All 39 isolates were analyzed by Ziehl-Nielsen stained smear, bacterial culture and submitted to rpoB partial gene sequencing for identification. The isolates were also evaluated for their susceptibility to amikacin, cefoxitin, clarithromycin, ciprofloxacin, doxycycline, tobramycin and sulfamethoxazole. RESULTS: Thirty-six isolates out of the confirmed cases were identified as... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Mycobacteria; Atypical mycobacterium infections microbiological analysis. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702011000500004 |
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