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Evaluation of Dietary Supplement Intake (Yeast Tablets) on Pregnant Albino Rats and Their Fetuses (Implications of Yeast Tablets on Rats & Fetuses) BABT
Omar,Amel Ramadan; El-Din,Eman Youssri Salah; Abdelrahman,Heba Ali; Mohamed,Hanan Ramadan.
ABSTRACT Histopathological studies in placenta, liver, kidney, apoptotic DNA damage and p53 mutation estimation of pregnant rats and their offspring exposed to dietary supplement yeast tablets, were carried out. Pregnant female albino rats were orally administrated yeast tablets at concentration 41.1 mg/kg during gestation period. Hematoxylin and eosin stained sections were used for examination. Neutral comet assay was performed to assess the apoptotic DNA damage and single strand conformational analysis was performed to screen the mutations inductions in p53 exons 7 and 8. Statistical analysis is applied to found the relation of apoptotic fraction in liver, kidney and placenta of pregnant rats and their offspring. Oral administration of yeast tablets to...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Alteration; Comet assay; Single strand conformational analysis; Yeast tablets.
Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132018000100420
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Implications arising from the use of Cymbopogen proximus ; proximal on placenta of pregnant Albino rats BABT
Omar,Amel Ramadan; El-Din,Eman Youssri Salah; Abdelrahman,Heba Ali.
ABSTRACT Halfa-bar (Cymbopogon proximus), is an aromatic grass widely growing in Upper Egypt. This herb is recommended for medical purposes as an effective diuretic, renal or abdominal antispasmodic agent. Objectives of this study: Evaluate the potential effects of Halfa-bar on the pregnant albino rats during the gestation period. Material and methods: The virgin female rats mated with male then the pregnant rats treated orally with Human Equivalent Dose (HED) of the proximol which equivalent 0.05 mg/ kg rat from 5th -18th Gestational Day (GD). At day 20 of pregnancy, all rats were anesthetized and killed to obtained maternal -fetal data (placenta). Results: The current study indicated that, there is statistically significant (P ≤ 0.05) reduction in the...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Cymbopogen proximus; Placenta; Rattus norvegicus.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100330
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