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| SILVA,DAYANE M.; MARTINS,JOSÉ L.R.; FLORENTINO,IZIARA F.; OLIVEIRA,DANILLO R.; FAJEMIROYE,JAMES O.; TRESNVENZOL,LEONICE M.F.; PAULA,JOSÉ R.; COSTA,ELSON A.. |
| ABSTRACT Memora nodosa is popularly known as "caroba" and widely found in the Cerrado regions of Brazil. In traditional medicine, the leaves and stems are used for the healing of external ulcer and the roots for abdominal pain. This study investigated the effect of ethanolic roots extract of Memora nodosa (EMN) on the gastric mucosa of mice. In the indomethacin induced gastric ulcer model, the treatments of the animals with EMN at doses of 100, 300 and 1000 mg/kg, p.o., markedly reduced the index of lesions. In the gastric ulcer models induced by ethanol and cold restraint-stress the previous treatment with EMN at dose of 300 mg/kg showed 69% and 43% of protection, respectively. Seven days after food-restriction, the animals treated with EMN (300 mg/kg... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Gastric lesion; Gastroprotection; Medicinal plants; Memora nodosa; Mucus; Traditional medicine. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000501819 |
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| FLORENTINO,IZIARA F.; NASCIMENTO,MARCUS VINÍCIUS M.; GALDINO,PABLINNY M.; BRITO,ADRIANE F. DE; ROCHA,FABIO F. DA; TONUSSI,CARLOS R.; LIMA,THEREZA CHRISTINA M. DE; PAULA,JOSÉ R. DE; COSTA,ELSON A.. |
| The Hydrocotyle umbellata L. is a specimen of the Araliaceae family popularly known as acariçoba. Its indications in folk medicine include treatment of skin ulcers, and rheumatism. The aim of this study was to evaluate the antinociceptive and anti-inflammatory activities of the ethanolic extract from acariçoba's underground parts (EEA). EEA reduced the nociceptive response of the animals as evaluated in the acetic acid-induced writhing test and in both phases of formalin test. EEA also presented a supraspinal analgesic activity by increasing the pain latency in the hot plate test. Moreover, EEA reduced the leukocytes migration and plasma extravasation to pleural cavity in the carrageenan-induced pleurisy, besides reducing the edema induced by carrageenan... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acariçoba; Anti-inflammatory; Antinociceptive; Biomedical Sciences; Hydrocotyle umbellata L. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652013000300987 |
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