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	Provedor de dados BJPS (1) Autor Araújo,Magali Benjamim de (1) Azevedo,Roberta de Cássia Pimentel (1) Bonfilio,Rudy (1) Favoretto,Lívia Botacini (1) Pereira,Gislaine Ribeiro (1) Palavra-chave Direct UV spectrophotometry (1) First-derivative UV spectrophotometry (1) Losartan potassium (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2010 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Comparative study of analytical methods by direct and first-derivative UV spectrophotometry for evaluation of losartan potassium in capsules BJPS Bonfilio,Rudy; Favoretto,Lívia Botacini; Pereira,Gislaine Ribeiro; Azevedo,Roberta de Cássia Pimentel; Araújo,Magali Benjamim de. Losartan potassium is an antihypertensive non-peptide agent, which exerts its action by specific blockade of angiotensin II receptors. The aim of the present study was the validation and application of analytical methods for the quality control of losartan potassium 50 mg in pharmaceutical capsules, using direct and first-derivative UV spectrophotometry. Based on losartan potassium spectrophotometric characteristics, a signal at 205 nm of the zero-order spectrum and a signal at 234 nm of the first-derivative spectrum, were found adequate for quantification. The results were used to compare these instrumental techniques. The linearity between the signals and concentrations of losartan potassium in the ranges of 3.0-7.0 mg L-1 and 6.0-14.0 mg L-1 for direct... Tipo: Info:eu-repo/semantics/article Palavras-chave: Losartan potassium; Direct UV spectrophotometry; First-derivative UV spectrophotometry. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000100017 Registros recuperados: 1 Primeira ... 1 ... Última

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