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	Provedor de dados Biol. Res. (1) Autor Felipe,Aledson V (1) Forones,Nora M (1) Kassab,Paulo (1) Pimenta,Célia A (1) Silva,Tiago D (1) Palavra-chave Gastric cancer (1) IL-8 (1) Polymorphism (1) Tipo do documento Journal article (1) Ano 2012 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última lnterleukin-8 gene polymorphism and susceptibility to gastric cancer in a brazilian population Biol. Res. Felipe,Aledson V; Silva,Tiago D; Pimenta,Célia A; Kassab,Paulo; Forones,Nora M. BACKGROUND: Studies have demonstrated that some polymorphisms in different interleukin genes may increase the risk of cancer. The aim of this study was to investigate the association between the IL-8 (rs4073) -251A/T gene polymorphism and the risk of gastric cancer (GC). PATIENTS AND METHODS: A case-control study was conducted on patients with noncardia gastric cancer. DNA was extracted from leukocytes and the IL-8 (rs4073) -251A/T polymorphism was analyzed by PCR-RFLP. Infection with Helicobacter pylori was investigated in the serum by ELISA. RESULTS: The sample consisted of 104 patients with GC and 196 controls. Cigarette smoking (P=0.007) and high fat intake (P=0.01) were more frequent in patients with GC. The proportion of patients infected with H.... Tipo: Journal article Palavras-chave: IL-8; Polymorphism; Gastric cancer. Ano: 2012 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602012000400007 Registros recuperados: 1 Primeira ... 1 ... Última

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