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| Vigani,Aline Gonzalez; Gonçales,Eduardo Sellan; Pavan,Maria Helena Postal; Genari,Flavia; Tozzo,Raquel; Lazarini,Maria Silvia Kroll; Fais,Viviane; Feltrin,Adriana; Gonçales,Neiva Sellan; Gonçales Jr,Fernando Lopes. |
| BACKGROUND: Pegylated interferon (Peg-IFN) and standard interferon (IFN) play a significant role in the treatment of hepatitis C virus (HCV) infection. Biosimilar standard IFN is widely available in Brazil for the treatment of HCV infection genotypes 2 or 3, but its efficacy compared to Peg-IFN is unknown. OBJECTIVE: To compare the sustained virological response (SVR) rates following treatment with biosimilar standard IFN plus ribavirin (RBV) versus Peg-IFN plus RBV in patients with HCV genotypes 2 or 3 infection. METHODS: A retrospective cohort study was conducted in patients with HCV genotypes 2 or 3 infection treated with biosimilar standard IFN plus RBV or with Peg-IFN plus RBV. SVR rates of the two treatments were compared. RESULTS: From January 2005... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Interferons; Hepatitis C; Treatment outcome. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000300003 |
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