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	Provedor de dados Biol. Res. (2) Autor Berríos,Soledad (2) Fernández-Donoso,Raúl (2) López-Fenner,Julio (2) Manterola,Marcia (2) Page,Jesús (2) Ayarza,Eliana (1) González,Marisel (1) Manieu,Catalina (1) Prieto,Zulita (1) Mais... Palavra-chave Bivalent associations (2) Mouse spermatocytes (2) Heterochromatin distribution (1) Nuclear architecture (1) Nuclear model (1) Robertsonian chromosomes (1) Mais... Tipo do documento Journal article (2) Ano 2014 (1) 2010 (1) País Chile (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Robertsonian chromosomes and the nuclear architecture of mouse meiotic prophase spermatocytes Biol. Res. Berríos,Soledad; Manieu,Catalina; López-Fenner,Julio; Ayarza,Eliana; Page,Jesús; González,Marisel; Manterola,Marcia; Fernández-Donoso,Raúl. BACKGROUND: The nuclear architecture of meiotic prophase spermatocytes is based on higher-order patterns of spatial associations among chromosomal domains from different bivalents. The meiotic nuclear architecture depends on the chromosome characteristics and consequently is prone to modification by chromosomal rearrangements. In this work, we consider Mus domesticus spermatocytes with diploid chromosome number 2n = 40, all telocentric, and investigate a possible modification of the ancestral nuclear architecture due to the emergence of derived Rb chromosomes, which may be present in the homozygous or heterozygous condition. RESULTS: In the 2n = 40 spermatocyte nuclei random associations mediated by pericentromeric heterochromatin among the 19 telocentric... Tipo: Journal article Palavras-chave: Robertsonian chromosomes; Mouse spermatocytes; Bivalent associations; Nuclear architecture. Ano: 2014 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100016 Model of chromosome associations in Mus domesticus spermatocytes Biol. Res. Berríos,Soledad; Manterola,Marcia; Prieto,Zulita; López-Fenner,Julio; Page,Jesús; Fernández-Donoso,Raúl. Understanding the spatial organization of the chromosomes in meiotic nuclei is crucial to our knowledge of the genome's functional regulation, stability and evolution. This study examined the nuclear architecture of Mus domesticus 2n=40 pachytene spermatocytes, analyzing the associations among autosomal bivalents via their Centromere Telomere Complexes (CTC). The study developed a nuclear model in which each CTC was represented as a 3D computer object. The probability of a given combination of associations among CTC was estimated by simulating a random distribution of 19 indistinguishable CTC over n indistinguishable "cells" on the nuclear envelope. The estimated association frequencies resulting from this numerical approach were similar to those obtained... Tipo: Journal article Palavras-chave: Bivalent associations; Nuclear model; Mouse spermatocytes; Heterochromatin distribution. Ano: 2010 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602010000300003 Registros recuperados: 2 Primeira ... 1 ... Última

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