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	Provedor de dados BJMBR (2) Autor Fernandes,T. (2) Oliveira,E.M. (2) Hashimoto,N.Y. (1) Soci,U.P.R. (1) Palavra-chave Renin-angiotensin system (2) ACE1 (1) ACE2 (1) AT1 receptor (1) Akt (1) Cardiac hypertrophy (1) Exercise training (1) MicroRNAs (1) Rat skeletal muscle (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2011 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Eccentric and concentric cardiac hypertrophy induced by exercise training: microRNAs and molecular determinants BJMBR Fernandes,T.; Soci,U.P.R.; Oliveira,E.M.. Among the molecular, biochemical and cellular processes that orchestrate the development of the different phenotypes of cardiac hypertrophy in response to physiological stimuli or pathological insults, the specific contribution of exercise training has recently become appreciated. Physiological cardiac hypertrophy involves complex cardiac remodeling that occurs as an adaptive response to static or dynamic chronic exercise, but the stimuli and molecular mechanisms underlying transduction of the hemodynamic overload into myocardial growth are poorly understood. This review summarizes the physiological stimuli that induce concentric and eccentric physiological hypertrophy, and discusses the molecular mechanisms, sarcomeric organization, and signaling pathway... Tipo: Info:eu-repo/semantics/article Palavras-chave: Exercise training; Cardiac hypertrophy; Renin-angiotensin system; AT1 receptor; Akt; MicroRNAs. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000900003 Characterization of angiotensin-converting enzymes 1 and 2 in the soleus and plantaris muscles of rats BJMBR Fernandes,T.; Hashimoto,N.Y.; Oliveira,E.M.. Angiotensin-converting enzymes 1 (ACE1) and 2 (ACE2) are key enzymes of the renin-angiotensin system, which act antagonistically to regulate the levels of angiotensin II (Ang II) and Ang-(1-7). Considerable data show that ACE1 acts on normal skeletal muscle functions and architecture. However, little is known about ACE1 levels in muscles with different fiber compositions. Furthermore, ACE2 levels in skeletal muscle are not known. Therefore, the purpose of this study was to characterize protein expression and ACE1 and ACE2 activities in the soleus and plantaris muscles. Eight-week-old female Wistar rats (N = 8) were killed by decapitation and the muscle tissues harvested for biochemical and molecular analyses. ACE1 and ACE2 activities were investigated by a... Tipo: Info:eu-repo/semantics/other Palavras-chave: Renin-angiotensin system; ACE1; ACE2; Rat skeletal muscle. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000900005 Registros recuperados: 2 Primeira ... 1 ... Última

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