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Effect of naringerin on biochemical parameters in the streptozotocin-induced diabetic rats BABT
Fernandes,Ana Angélica Henrique; Novelli,Ethel Lourenzi Barbosa; Fernandes Junior,Ary; Galhardi,Cristiano Machado.
Amongst the numerous co-adjuvant therapies which could influence the incidence and progression of diabetic complications, antioxidants and flavonoids are currently being tested in clinical trials. We investigated the effect of naringerin on biochemical parameters in streptozotocin-induced (STZ - 60 mg/kg, i.p.) diabetic rats. Male rats were divided into four groups: G1: untreated controls; G2: normal rats receiving naringerin; G3: untreated diabetics; G4: diabetics rats receiving naringerin. The naringerin (50mg/kg, i.p,) decreased the hyperglycaemia and hyperlipidaemia associated with STZ-diabetes. The concentrations of serum insulin in treated diabetic rats tended to be increased. Naringerin treatment prevents STZ-induced changes in the activities of...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Naringerin; Hypoglycaemic activity; Streptozotocin; Diabetes mellitus; Aminotransferases; Hepatic; Cardiac tissues.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132009000100007
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Synergistic effect of propolis and antibiotics on the Salmonella Typhi BJM
Orsi,Ricardo de Oliveira; Sforcin,José Maurício; Funari,Silvia Regina Cunha; Fernandes Junior,Ary; Bankova,Vassya.
The goal of this work was to investigate a possible synergistic effect between ethanolic extracts of propolis from Brazil and Bulgaria and some antibiotics (Amoxicillin, Ampicillin and Cefalexin) against Salmonella Typhi. Brazilian and Bulgarian propolis showed an antibacterial action, but the sample from Bulgaria was shown to be more efficient. Both samples showed a similar synergistic effect with these antibiotics. One may conclude that the propolis samples show an important antibacterial action, as well as a synergistic effect with antibiotics against Salmonella Typhi.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Propolis; Antimicrobial activity; Antibiotics; Synergistic effect.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000200002
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Evaluation of the Diramic system for urine cultures BJM
Higuchi,Cristian Kendi; Corrêa,Carlos Roberto; Rall,Vera Lucia Mores; Fernandes Junior,Ary.
The use of the Diramic system in microbiological diagnosis of urinary tract infections (UTI) was evaluated. This system was developed at the National Center for Scientific Research of Cuba, and it reads turbidimetric changes of microbial growth in culture media at 37ºC incubated for 4 hours. A total of 396 urine specimens were tested in the Laboratory of Microbiology of the School of Medicine - UNESP, Brazil using the Diramic system and the counting of colony forming units per urine millimeter (calibrated loop) as the reference method. The coincidence rate between the two methods was 96.46% (382 urine samples), and the differences in results were not significant (p<0.05). Sensitivity and specificity rates were 84.37% and 98.80%, respectively. False...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Diramic; Calibrated loop; Urinary tract infection; Urine cultures.
Ano: 2006 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822006000300005
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Antibacterial activity of medicinal plant extracts BJM
Ushimaru,Priscila Ikeda; Silva,Mariama Tomaz Nogueira da; Di Stasi,Luiz Claudio; Barbosa,Luciano; Fernandes Junior,Ary.
The present study aimed at evaluating the in vitro antimicrobial activity of methanolic extracts of some medicinal plants against Escherichia coli, Salmonella Typhimurium, Staphylococcus aureus and Enterococcus sp. The methanolic extract of Caryophyllus aromaticus presented the highest anti-S. aureus activity and was effective against all bacterial strains tested.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Medicinal plants; Antibacterial activity; Minimal Inhibitory Concentration.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000400024
Registros recuperados: 4
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