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The plant cell cycle: Pre-Replication complex formation and controls Genet. Mol. Biol.
Brasil,Juliana Nogueira; Costa,Carinne N. Monteiro; Cabral,Luiz Mors; Ferreira,Paulo C. G.; Hemerly,Adriana S..
Abstract The multiplication of cells in all living organisms requires a tight regulation of DNA replication. Several mechanisms take place to ensure that the DNA is replicated faithfully and just once per cell cycle in order to originate through mitoses two new daughter cells that contain exactly the same information from the previous one. A key control mechanism that occurs before cells enter S phase is the formation of a pre-replication complex (pre-RC) that is assembled at replication origins by the sequential association of the origin recognition complex, followed by Cdt1, Cdc6 and finally MCMs, licensing DNA to start replication. The identification of pre-RC members in all animal and plant species shows that this complex is conserved in eukaryotes...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pre-replication complex; A. thaliana; Cell cycle.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000200276
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