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| Flores,Mariana Martins; Mazaro,Renata Dalcol; Langohr,Ingeborg Maria; Roy,Alma; Strother,Keith; Fighera,Rafael Almeida. |
| ABSTRACT: The use of histologic classification by a 2-tier grading system only, immunohistochemistry (IHC) for KIT and Ki-67 and polymerase chain reaction (PCR) for internal tandem duplications (ITD) on exon 11 has improved the prognostication of canine cutaneous mast cell tumors (CCMTs) particularly in the United States. However, these techniques are not commonly used in most Brazilian laboratories. Likewise, no studies, to date, have investigated the occurrence of ITD in CCMTs from the country. Thus, this study tested the 2-tier grading system, the immunohistochemistry for KIT and Ki-67 and the PCR for exon 11 in a group of Brazilian CCMTs with the goal of investigating the applicability of these tests in a Brazilian laboratory. Of the 39 CCMTs, 69.2%... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Immunohistochemistry; Ki-67; Mutations; PCR; Mast cell tumor.. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782016001001804 |
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| Ripplinger,Angel; Silva,Ana Paula da; Wrzesinski,Mathias Reginatto; Ferrarin,Dênis Antonio; Schwab,Marcelo Luís; Pozzobon,Ricardo; Flores,Mariana Martins; Thompson,Ruth Pamela; Mario,Fabiana; Mazzanti,Alexandre. |
| ABSTRACT: The aim of this report was to describe a case of aortic thrombosis (AT) secondary to chronic lymphocytic leukemia (CLL). Although, different types of neoplasms are described as possible causes of aortic thrombosis, CLL was not yet considered. The dog showed signs of lameness that worsened with exercise. The diagnosis of AT was made by ultrasound examination. The diagnosis of CLL was made by necropsy, which showed the presence of small lymphocytes with the appearance of mature lymphocytes in the bone marrow, spleen, liver and kidneys. The importance of including CLL in the possible causes of AT in dogs, in addition to the suspicion of AT in cases of neuromuscular disease, was highlighted. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Canine; Lymphoid leukemia; Ischemic neuromyopathy; Thrombus. |
| Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782020000400601 |
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| Aiello,Graciane; Ripplinger,Angel; Schwab,Marcelo Luís; Ferrarin,Dênis Antonio; Rauber,Júlia da Silva; Areco,Walter Cardozo; Flores,Mariana Martins; Mazzanti,Alexandre. |
| ABSTRACT: A 14-year-old female Dachshund was referred to a veterinary hospital with a history and signalment of head pressing, compulsive walking, and right circling. At ophthalmologic examination, a mature cataract and absence of photomotor reflex in the right eye were observed. The neurological exam revealed multifocal encephalic signs. At necropsy, a conical solid tan mass was observed involving the right optic nerve throughout its extension to the optic chiasm. Histopathological findings confirmed a retrobulbar papillary meningioma, considered rare and seldom included as differential diagnosis in patients with neurological signs. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ocular neoplasm; Papillary meningioma; Central nervous system; Canine. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782019000700551 |
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| Panziera,Welden; Bianchi,Ronaldo Michel; Pereira,Paula Reis; Flores,Mariana Martins; Togni,Monique; Pereira,Roberta Carneiro da Fontoura; Corte,Flávio De La; Fighera,Rafael Almeida. |
| ABSTRACT: This report described clinical, epidemiological, and pathological aspects of ischemic myelopathy caused by fibrocartilaginous embolism (FCE) in a 10-year-old, mixed breed gelding. Clinically, the horse presented acute hind limbs paralysis, with a clinical course of approximately 24 hours. At necropsy, no gross lesions were observed. Cross-sections of the spinal cord revealed focally extensive areas of malacia from the T10 to L4 segments. Focally extensive areas of liquefactive necrosis involving the gray matter and adjacent white matter were observed on histologic sections. The lumen of multiple blood vessels in the periphery of the necrotic areas was occluded by fibrocartilaginous emboli that strongly stained with alcian blue. Clinical signs,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Equine diseases; Neurological disorder; Ischemic myelopathy; Pathology. |
| Ano: 2018 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782018000200502 |
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