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| Desvignes, T.; Fostier, A.; Fauvel, Christian; Bobe, J.. |
| The Nme gene family, also known as Nm23 or NDPK, is a very ancient gene family that can be found in all kingdoms of life. In the late eighties, a gene of the Nme family, NME1, was identified as the first metastatic suppressor gene, resulting in a major interest for this family. Due to the complexity of the family, the need for a unified and evolutionary-supported gene nomenclature was recently stressed by the scientific community. Based on a complete evolutionary history study of the gene family in metazoans and vertebrates, a unified nomenclature was recently proposed and accepted by gene nomenclature consortia. In addition to its well-documented role in tumor metastasis, members of the Nme family are also involved in a wide variety of cellular and... |
| Tipo: Text |
Palavras-chave: Nm23; NDPK; RP2; Teleost; Oocyte; Ovary. |
| Ano: 2013 |
URL: http://archimer.ifremer.fr/doc/00133/24466/22504.pdf |
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| Bennetau-pelissero, C.; Kaushik, S.; Sumpter, J.; Fostier, A.; Le Gac, F.; Valotaire, Y.; Davail-cuisset, B.; Le Menn, F.. |
| The development of a new sex determination test of Siberian sturgeon based on vitellogenin (VTG) detection in plasma led to identify this complex factor in plasma from male, female and immature fish of this species. The hypothesis of an estrogenic contamination from an environmental origin was confirmed by a test based on the feeding of fish on different diets. In control fish fed with a casein-based diet free of any estrogenic compound, VTG disappeared from the plasma within 15 weeks. With a fish meal-based diet as well as with a soy-based diet, the plasma VTG levels raised significantly. Later, an estrogenic effect of soy orally administrated was demonstrated in vivo in the rainbow trout although it is lower than that observed in sturgeon. Soya is known... |
| Tipo: Text |
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| Ano: 1998 |
URL: https://archimer.ifremer.fr/doc/00480/59131/61759.pdf |
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