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Utescher,Carla Lílian de Agostini; Franzolin,Marcia Regina; Trabulsi,Luiz Rachid; Gambale,Valderez. |
The aim of the present work was to evaluate an environmental monitoring program for clean rooms, or classified environments, involved in the filling and quality control of biological products produced by Butantan Institute, São Paulo, Brazil. This monitoring established the quantification, characterization and seasonality of the microorganisms in air and operators and, moreover, determined the alert and action limits. The total detectable microbial number showed some contrasts in installed air purification systems and in the operational impact on adopted procedures. The typical microbial population consisted of Staphylococcus sp, Micrococcus sp, Bacillus sp and Penicillium sp. The highest microorganism concentration occurred during summer and springtime.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Environmental control; Viable particles; Clean rooms; Alert and action limits. |
Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822007000400023 |
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Kazuma,Kohei; Ando,Kenji; Nihei,Ken-ichi; Wang,Xiaoyu; Rangel,Marisa; Franzolin,Marcia Regina; Mori-Yasumoto,Kanami; Sekita,Setsuko; Kadowaki,Makoto; Satake,Motoyoshi; Konno,Katsuhiro. |
Abstract Background: Among the hymenopteran insect venoms, those from social wasps and bees - such as honeybee, hornets and paper wasps - have been well documented. Their venoms are composed of a number of peptides and proteins and used for defending their nests and themselves from predators. In contrast, the venoms of solitary wasps and bees have not been the object of further research. In case of solitary bees, only major peptide components in a few venoms have been addressed. Therefore, the aim of the present study was to explore the peptide component profile of the venom from the solitary bee Xylocopa appendiculata circumvolans by peptidomic analysis with using LC-MS. Methods: A reverse-phase HPLC connected to ESI-OrbiTrap MS was used for LC-MS.... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Peptidomic analysis; LC-ESI-MS; Solitary bee; Venom; Linear cationic α-helical peptide. |
Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992017000100316 |
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