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| Lopes,P.R.; Moreira,M.C.S.; Marques,S.M.; Pinto,I.S.J.; Macedo,L.M.; Silva,C.C.; Freiria-Oliveira,A.H.; Rebelo,A.C.S.; Reis,A.A.S.; Rosa,D.A.; Ferreira-Neto,M.L.; Castro,C.H.; Pedrino,G.R.. |
| The present study sought to determine cardiovascular effects of aerobic training associated with diminazene aceturate (DIZE), an activator of the angiotensin converting enzyme 2, in spontaneously hypertensive rats (SHRs). Male SHRs (280–350 g) were either subjected to exercise training or not (sedentary group). The trained group was subjected to 8 weeks of aerobic training on a treadmill (five times a week, lasting 60 min at an intensity of 50–60% of maximum aerobic speed). In the last 15 days of the experimental protocol, these groups were redistributed into four groups: i) sedentary SHRs with daily treatment of 1 mg/kg DIZE (S+D1); ii) trained SHRs with daily treatment of 1 mg/kg DIZE (T+D1); iii) sedentary SHRs with daily treatment of vehicle (S+V); and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Intrinsic heart rate; Diminazene aceturate; Aerobic training; Double autonomic blockade; Renin-angiotensin system. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000900603 |
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