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| Freitas,E. S.; Leite,E. D.; Silva,A. E.; Ocarino,N. M.; Ferreira,E.; Gomes,M. G.; Cassali,G. D.; Serakides,R. |
| The main purpose of this study was to investigate the effect of thyroxine and PTU in ascitic Ehrlich tumor cells. Tumor was implanted in 30 female mice distributed in three groups: treated with PTU, treated with thyroxine and control. Each group received an intraperitoneal injection of neoplastic cells, pre-incubated with sterile solutions of PTU, thyroxine and distilled water, respectively. On the fifth and seventh days after inoculation, animals received an intraperitoneal injection of the respective solutions. On the tenth day after inoculation, animals were sacrificed. Volume of ascitic liquid, number of neoplastic cells/ml and percentage of viable cells were determined. Ascitic liquid smears were carried out for tumor cytological evaluation. There was... |
| Tipo: Journal article |
Palavras-chave: Cytology; Ehrlich tumor; Mouse; NORs; Propylthiouracil; Thyroxine. |
| Ano: 2006 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500024 |
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