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	Provedor de dados BJMBR (2) Autor Fronza,M. (2) Andrade,S.S. (1) Bogusz,S. (1) Dalmora,S.L. (1) Figueira,M.M. (1) Guidoni,M. (1) Rafferty,B. (1) Ramos,A.S. (1) Scherer,R. (1) Schmidt,C.A. (1) Schmitt,E.F.P. (1) de Almeida,L.C. (1) de Christo Scherer,M.M. (1) Mais... Palavra-chave Anti-inflammatory (1) Bioassay (1) Fatty acids (1) Nitric oxide (1) Normocythemic mice (1) Polycythemia (1) Recombinant human erythropoietin (1) Reticulocyte counting (1) Scratch assay (1) Skin care (1) Vegetable oil blend (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2019 (1) 2003 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Biological evaluation of recombinant human erythropoietin in pharmaceutical products BJMBR Ramos,A.S.; Schmidt,C.A.; Andrade,S.S.; Fronza,M.; Rafferty,B.; Dalmora,S.L.. The potencies of mammalian cell-derived recombinant human erythropoietin pharmaceutical preparations, from a total of five manufacturers, were assessed by in vivo bioassay using standardized protocols. Eight-week-old normocythemic mice received a single subcutaneous injection followed by blood sampling 96 h later or multiple daily injections with blood sampling 24 h after the last injection. Reticulocyte counting by microscopic examination was employed as the end-point using the brilliant cresyl blue or selective hemolysis methods, together with automated flow cytometry. Different injection schedules were investigated and dose-response curves for the European Pharmacopoeia Biological Reference Preparation of erythropoietin were compared. Manual and... Tipo: Info:eu-repo/semantics/article Palavras-chave: Recombinant human erythropoietin; Bioassay; Polycythemia; Reticulocyte counting; Normocythemic mice. Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003001100014 Fatty acid composition of vegetable oil blend and in vitro effects of pharmacotherapeutical skin care applications BJMBR Guidoni,M.; de Christo Scherer,M.M.; Figueira,M.M.; Schmitt,E.F.P.; de Almeida,L.C.; Scherer,R.; Bogusz,S.; Fronza,M.. Vegetable oils have been used for a plethora of health benefits by their incorporation in foods, cosmetics, and pharmaceutical products, especially those intended for skin care. This study aimed to investigate the cutaneous benefits of a vegetable oil blend (VOB) formulation and its fatty acid composition. The anti-inflammatory activity was studied in macrophages of RAW 264.7 cells by investigating the release of nitric oxide (NO), superoxide anion generation (O2-), tumor necrosis factor-alpha (TNF-α), and interleukin 6 (IL-6). ABTS cation radical scavenging capacity assay, ferric reducing antioxidant potential (FRAP), 2,2-diphenyl-1-picrylhydrazyl (DPPH), and NO free radical scavenging assays were used to evaluate the antioxidant activity. VOB was tested... Tipo: Info:eu-repo/semantics/article Palavras-chave: Vegetable oil blend; Skin care; Fatty acids; Anti-inflammatory; Nitric oxide; Scratch assay. Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000200609 Registros recuperados: 2 Primeira ... 1 ... Última

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