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| Göze,I; Göze,ÖF; Yelkovan,I; Çetinus,ŞA; Saygin,H; Ercan,N. |
| ABSTRACT Essential oil of plants called Juniperus excelsa Bieb. (JE), Origanum minutiflorum O. Schwarz and P.H. Davis (OM) were used in this study. In order to determine experimental doses, LD50 values of essential oils were determined on mice. Taking into consideration the LD30 range, the experimental toxic doses were calculated for each rat (rat/kg). The toxic dosages thus determined were adapted to rats for active substances (rat/kg). Using commercially available pure virgin olive oil (VOO) as the solvent and diluting agent, OM oil (n=10), JE fruitoil (n=10), carvacrol (CRV) (n=10), VOO (n=10) and normal saline SF (n=8) were administered on the basis of 12 days into intraperitoneal (IP). Enzyme activities of Glucose-6-Phosphate dehydrogenase (G6PDH),... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brain histopathology antioxidant enzymes Juniperus excelsa kidney; Liver Origanum minutiflorum. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2017000200333 |
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| Göze,I; Erşan,S; Aydin,H; Ercan,N; Dönmez,E. |
| ABSTRACT The aim of this study was to determine the LD30 values of the essential oils of Origanum minutiflorum He Schwarz-PH Davis (OM) and Juniperus excelca by Bieb.subsp. Excel (JE) in vivo investigation on the effects of malondialdehyde (MDA), vitamin C and some biochemical parameters. In this, study the essential oils of OM and JE plants were used. LD50 values of the essential oils were determined by using rats. OM (n=10), JE (n=10), carvacrol (n=10) which dissolve in olive oil were used as experimental group and as control group saline (SF) (n=8) and solvent Olive oil (n=10) were used and applied intraperitoneal on rats for 12 days in LD30 dosages. In the end of 12 days, Vit-C, malondialdehyde (MDA) and routine biochemical analyses were studied on... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Origanumminutiflorum O Schwarz-PH Davis; Juniperusexcelca Bieb.subsp.excelca; Essential oil; Vitamin C; Malondialdehyde; Enzyme. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2019000200306 |
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