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| Güez,Camila Martins; Waczuk,Emily Pansera; Pereira,Karina Braccini; Querol,Marcus Vinícius Morini; Rocha,João Batista Teixeira da; Oliveira,Luís Flávio Souza de. |
| The use of plants as a source of palliative or cure for pathological conditions is quite common worldwide. Xanthium spinosum (Asteraceae), popularly known in Brazil as 'espinho de carneiro', is an annual weed from South America, which has been used by empiric medicine to treat neoplasias. Owing to the extensive use of the above-mentioned plant and to the lack of reports about the real effects of its infusion, current study evaluated the genotoxic potential of its aqueous extract at concentrations 0.02 g L-1, 0.1 g L-1 and 0.2 g L-1 by fish micronucleus test and by comet human leukocytes assay. The micronucleus test featured at least 50 cells with micronuclei to every 2,000 cells scored, as a mutagenic parameter. The comet assay was used as a parameter for... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Xanthium spinosum/pharmacognosy; Xanthium spinosum/aqueous extract; Xanthium spinosum/genotoxicity; Fish micronucleus assay; Comet assay. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502012000300013 |
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| Güez,Camila Martins; Souza,Raul Oliveira de; Fischer,Paula; Leão,Maria Fernanda de Moura; Duarte,Jonathaline Apollo; Boligon,Aline Augusti; Athayde,Margareth Linde; Zuravski,Luísa; Oliveira,Luís Flávio Souza de; Machado,Michel Mansur. |
| ABSTRACT Ocimum is one of the most important genera of the Lamiaceae family. Several studies about basil and its popular use reveal many characteristics of the herb, including its use as antioxidant, anti-aging, anti-inflammatory, anti-carcinogenic, anti-microbial, and cardiovascular agents, among others. In this paper, we evaluated genotoxic, oxidative, and anti-inflammatory parameters from the extract of Ocimum basilicum in different concentrations, using human leukocytes cultures exposed to challenging agents. Our results confirm that the O. basilicum extract acts as an antioxidant and effectively reverts or subjugates the effects of high oxidizing agents such as hydrogen peroxide. These actions are attributed to its composition, which is rich in... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Ocimum basilicum/evaluation; Ocimum basilicum/genotoxic effects; Ocimum basilicum/anti-inflammatory properties; Medicinal plants/study.. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502017000100606 |
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