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	Provedor de dados Biol. Res. (1) Autor GHATPANDE,SATISH (1) SHAFIQ,SAIYID (1) SIDDIQUI,M.A.Q. (1) Palavra-chave Cardiogenesis (1) Cardiomyopathy (1) Myosin light chains (1) Tissue culture (1) Tipo do documento Journal article (1) Ano 2001 (1) País Chile (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Ventricular Myosin Light Chain-2 Gene Expression in Developing Heart of Chicken Embryos Biol. Res. GHATPANDE,SATISH; SHAFIQ,SAIYID; SIDDIQUI,M.A.Q.. Recent gene knock-out studies in mice have suggested that ventricular myosin light chain-2 (vMLC2) has a role in the regulation of cardiogenic development and that perturbation in expression of vMLC2 is linked to the onset of dilated cardiomyopathy. In an attempt to develop an avian model for such studies, we examined the expression pattern of vMLC2 in chicken embryos at various stages and analyzed the effect of antisense oligonucleotide-mediated interference of vMLC2 function in cultures of whole embryos. Our results showed vMLC2 to be a specific marker for ventricular chamber throughout chicken embryonic development and antisense vMLC2 treatment of primitive streak stage (stage 4) embryos to produce pronounced dilation of heart tube with severe... Tipo: Journal article Palavras-chave: Cardiogenesis; Cardiomyopathy; Myosin light chains; Tissue culture. Ano: 2001 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000100009 Registros recuperados: 1 Primeira ... 1 ... Última

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