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Top 10 evidence-based recommendations from the Brazilian Society of Infectious Diseases for the Choosing Wisely Project BJID
Pasqualotto,Alessandro C.; Almeida,Camila S.; Kliemann,Dimas A.; Barcellos,Guilherme B.; Queiroz-Telles,Flávio; Abdala,Edson; Resende,Mariangela; Batista,Filipe P.; Vidal,José E.; Rocha,Jaime; Raboni,Sonia M.; Cimerman,Sergio; Gales,Ana C..
ABSTRACT The Choosing Wisely Initiative aims to collect statements from medical societies all over the world on medical interventions that result in no benefit to patients, with the potential to cause harm. In this article we present the views of the Diagnostic Laboratory Group at the Brazilian Society of Infectious Diseases (SBI). Ten experts from SBI were asked to list 10 diagnostic tests that were perceived as unnecessary in the field of infectious diseases. After voting for the more relevant topics, a questionnaire was sent to all SBI members, in order to select for the most important items. A total of 482 votes were obtained, and the top 10 results are shown in this manuscript. The Choosing Wisely statements of SBI should facilitate clinical practice...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Choosing wisely; Quality; Safety; Infectious diseases; Microbiology; Diagnostic tests; Healthcare administration.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702019000500331
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Antimicrobial susceptibility of gram-positive bacteria isolated in brazilian hospitals participating in the SENTRY Program (2005-2008) BJID
Gales,Ana C.; Sader,Helio S.; Ribeiro,Julival; Zoccoli,Cassia; Barth,Afonso; Pignatari,Antonio C..
We report the antimicrobial susceptibility patterns of the most frequently isolated Gram-positive bacteria in the Brazilian hospitals participating in the SENTRYAntimicrobial Surveillance Program. The strains were consecutively collected (one per patient) between January 2005 and September 2008 and susceptibility tested by reference broth microdilution methods at the JMI Laboratories (North Liberty, Iowa, USA). A total of 3,907 Gram-positive cocci were analyzed. The Gram-positive organisms most frequently isolated from bloodstream infections were Staphylococcus aureus (2,218 strains; 20.2% of total), coagulase-negative staphylococci (CoNS; 812 strains [14.7%]), and Enterococcus spp. (754 strains; 5.0%). S. aureus ranked first (28.1%) and Enterococcus...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial resistance; SENTRY; Nosocomial infections; Brazil.
Ano: 2009 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000200004
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Evaluation of the Susceptibility profiles, genetic similarity and presence of qnr gene in Escherichia coli resistant to ciprofloxacin isolated in Brazilian hospitals BJID
Pereira,Andrea S.; Andrade,Soraya S.; Monteiro,Jussimara; Sader,Helio S.; Pignatari,Antonio C.C.; Gales,Ana C..
Increasing quinolone resistance has been reported worldwide, mainly among clinical isolates of Escherichia coli. The objectives of this study were to determine the susceptibility profile, the genetic relatedness, and the prevalence of the qnr gene among ciprofloxacin-resistant Escherichia coli isolated from distinct Brazilian hospitals. A total of 144 ciprofloxacin-resistant Escherichia coli were isolated from 17 Brazilian hospitals between January/2002 and June/2003. The antimicrobial susceptibility testing was performed by microdilution according to NCCLS. The presence of the qnr gene was initially screened by colony blotting, and then confirmed by PCR followed by DNA sequencing. Ninety-five urinary ciprofloxacin-resistant Escherichia coli were further...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Quinolone resistance; Escherichia coli; PFGE; Qnr.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702007000100011
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In vitro activity of tigecycline, a new glycylcycline, tested against 1,326 clinical bacterial strains isolated from Latin America BJID
Gales,Ana C.; Jones,Ronald N.; Andrade,Soraya S.; Pereira,Andrea S.; Sader,Hélio S..
The in vitro activity of tigecycline (former GAR-936), a new semisynthetic tetracycline, was evaluated in comparison with tetracycline and other antimicrobial agents. MATERIAL AND METHODS: A total of 1,326 contemporary clinical isolates collected from the Latin American region were collected in 2000-2002 period and tested with microdilution broth according to the CLSI guidelines. The bacterial pathogens evaluated included Staphylococcus aureus (505), Streptococcus pneumoniae (269), coagulase-negative staphylococci (CoNS; 227), Haemophilus influenzae (129), Enterococcus spp. (80), Moraxella catarrhalis (54), beta-haemolytic streptococci (28), viridans group streptococci (26), and Neisseria meningitidis (8) RESULTS:Tigecycline demonstrated excellent activity...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial susceptibility; Tigecycline; Latin America and SENTRY.
Ano: 2005 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702005000500001
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Emergence of Klebsiella pneumoniae-producing KPC-2 carbapenemase in Paraíba, Northeastern Brazil BJID
Fehlberg,Lorena C.C.; Carvalho,Albalucia M.C.; Campana,Eloiza H.; Gontijo-Filho,Paulo P.; Gales,Ana C..
The emergence of KPC-2 producing K. pneumoniae in hospitalized patients at the intensive care unit (ICU) of a teaching hospital located in the city of João Pessoa, Paraíba, Brazil, is reported. Seven carbapenem-resistant K. pneumoniae recovered from different body sites of infection were analyzed. Most isolates showed a multidrug-resistance phenotype. Genotypic analysis demonstrated the presence of two genotypes, with the predominance of genotype A, which belongs to ST 437. These isolates also carry the encoding genes of five other betalactamases.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Beta-lactam resistance; Modified Hodge test; Carbapenem resistance; Enterobacteriaceae.
Ano: 2012 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702012000600013
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SENTRY antimicrobial surveillance program report: latin american and brazilian results for 1997 through 2001 BJID
Sader,Helio S.; Jones,Ronald N.; Gales,Ana C.; Silva,Juliana B.; Pignatari,Antonio C..
The alarming emergence and spread of antimicrobial resistance among common bacteria threatens the effectiveness of therapy for many infections. Surveillance of antimicrobial resistance is essential to identify the major problems and guide adequate control measures. Several resistance surveillance programs have been implemented in North America and Europe in the last decade; however, very few programs have assessed antimicrobial resistance in Latin American countries. The SENTRY Antimicrobial Surveillance Program was initiated in 1997 and represents the most comprehensive surveillance program in place at the present time worldwide. The SENTRY Program collects consecutive isolates from clinically documented infections in more than 80 medical centers...
Tipo: Info:eu-repo/semantics/article Palavras-chave: SENTRY; Antimicrobial resistance; Nosocomial infection; Surveillance; Latin America.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000100004
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Susceptibility rates in Latin American nations: report from a regional resistance surveillance program (2011) BJID
Jones,Ronald N.; Guzman-Blanco,Manuel; Gales,Ana C.; Gallegos,Belisario; Castro,Aura Lucia Leal; Martino,Marines Dalla Valle; Vega,Silvio; Zurita,Jeannete; Cepparulo,Mario; Castanheira,Mariana.
OBJECTIVE: To establish a resistance (R) surveillance program monitoring antimicrobial susceptibility patterns in Latin America (LATAM; Argentina [ARG], Brazil [BRA], Chile, Colombia [CBA], Costa Rica, Ecuador [ECU], Guatemala [GUA], Mexico [MEX], Panama [PAN], Peru, and Venezuela [VEN]). METHODS: In 2011, 4979 organisms were collected from 11 nations (20 laboratories) for susceptibility testing in a central laboratory design. Antimicrobials were tested by CLSI methods and results interpreted by CLSI and EUCAST breakpoints. Most common Gram-positive (Staphylococcus aureus [SA, 921], other staphylococci [CoNS; 299], enterococci [218], Streptococcus pneumoniae [SPN; 182], β-haemolytic streptococci [115]) and Gram-negative (E. coli [EC; 644], Klebsiella spp....
Tipo: Info:eu-repo/semantics/article Palavras-chave: Latin America; Surveillance; Resistance; ESBL; Β-Lactamases.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702013000600009
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Ability of Latin America laboratories to detect antimicrobial resistance patterns: experience of the SENTRY antimicrobial surveillance program (1997-2000) BJID
Mendes,Rodrigo E.; Reis,Adriana O.; Gales,Ana C.; Jones,Ronald N.; Sader,Hélio S..
The accuracy of antimicrobial susceptibility tests is a crucial step for the clinical management of patients with serious infections. They must be reliable and precise because they will guide antimicrobial therapy. Our main objective was to compare the results of susceptibility testing performed by the SENTRY coordinator laboratory with those reported by the participating Latin American medical centers. A total of 10,277 bacterial isolates were tested by the reference broth microdilution method at the coordinator laboratory in the United States. The tests were performed and interpreted following the National Committee for Clinical Laboratory Standards (NCCLS) recommendations. Ten antimicrobial agent-organism combinations were analyzed. The susceptibility...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Antimicrobial susceptibility test; Antimicrobial resistance pattern; Quality assurance.
Ano: 2003 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702003000500001
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Carbapenem-resistant Pseudomonas aeruginosa outbreak in an intensive care unit of a teaching hospital BJID
Gales,Ana C.; Torres,Patrícia L.; Vilarinho,Dominique S. O.; Melo,Renata S.; Silva,Claudinéia F. L.; Cereda,Rosângela F..
The genetic similarity of carbapenem-resistant Pseudomonas aeruginosa strains isolated in the Hospital Universitário São Francisco, Bragança Paulista, São Paulo, Brasil, was evaluated by pulsed field gel electrophoresis (PFGE). A unique clone was detected among 5 of 7 isolates, suggesting that cross-contamination might have played a role in the spread of carbapenem-resistant P. aeruginosa strains. Interestingly, a similar PFGE pattern was encountered in a P. aeruginosa strain isolated from Hospital São Paulo that was used as a PFGE control.
Tipo: Info:eu-repo/semantics/article Palavras-chave: Pseudomonas aeruginosa; PFGE; Carbapenem.
Ano: 2004 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702004000400001
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Pathogen frequency and resistance patterns in Brazilian hospitals: summary of results from three years of the SENTRY antimicrobial surveillance program BJID
Sader,Helio S.; Gales,Ana C.; Pfaller,Michael A.; Mendes,Rodrigo E.; Zoccoli,Cássia; Barth,Afonso; Jones,Ronald N..
BACKGROUND: Pathogen frequency and resistance patterns may vary significantly from country to country and also in different hospitals within a country. Thus, regional surveillance programs are essential to guide empirical therapy and infection control measures. METHODS: Rank order of occurrence and antimicrobial susceptibility of pathogenic species causing bloodstream infections (BSI), lower respiratory tract infections (LRTI), wound or skin and soft tissue infections (WSSTI), and urinary tract infections (UTI) in hospitalized patients were determined by collecting consecutive isolates over a specified period of time, as part of the SENTRY Antimicrobial Resistance Surveillance Program (SENTRY). All isolates were tested by reference broth microdilution....
Tipo: Info:eu-repo/semantics/article Palavras-chave: SENTRY; Antimicrobial resistance; Nosocomial infection; Surveillance program.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400006
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Online continuing interprofessional education on hospital-acquired infections for Latin America BJID
Medina-Presentado,Julio C.; Margolis,Alvaro; Teixeira,Lucia; Lorier,Leticia; Gales,Ana C.; Pérez-Sartori,Graciela; Oliveira,Maura S.; Seija,Verónica; Paciel,Daniela; Vignoli,Rafael; Guerra,Silvia; Albornoz,Henry; Arteta,Zaida; Lopez-Arredondo,Antonio; García,Sofía.
Abstract Introduction: Latin America is a large and diverse region, comprising more than 600 million inhabitants and one million physicians in over 20 countries. Resistance to antibacterial drugs is particularly important in the region. This paper describes the design, implementation and results of an international bi-lingual (Spanish and Portuguese) online continuing interprofessional interactive educational program on hospital-acquired infections and antimicrobial resistance for Latin America, supported by the American Society for Microbiology. Methods: Participation, satisfaction and knowledge gain (through pre and post tests) were used. Moreover, commitment to change statements were requested from participants at the end of the course and three...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Internet; Continuing education; Interprofessional education; MOOC; Hospital-acquired infections; Latin America.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702017000200140
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Antimicrobial activity of linezolid against Gram-positive cocci isolated in Brazil BJID
Sader,Helio S.; Gales,Ana C.; Jones,Ronald N..
The new oxazolidinone linezolid and other antimicrobial agents used to treat Gram-positive infections were tested against 1,585 Gram-positive cocci; 1,260 staphylococci and enterococci isolates from patients hospitalized in Brazilian hospitals, and 325 S. pneumoniae isolates for patients with community acquired infections. Susceptibility testing was performed using broth microdilution according to NCCLS procedures. Linezolid was the most active compound and the only drug that inhibited 100% of the isolates at the susceptible breakpoint (< 4 mg/mL). Resistance to vancomycin was very rare (99.9% susceptibility), and both quinupristin/dalfopristin and gatifloxacin were active against approximately 90% of the strains evaluated. All other compounds inhibited...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gram-positive cocci; Oxazolidinones; Antimicrobial resistance; Linezolid; Vancomycin resistance; Nosocomial infections.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400002
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Frequency of plasmid-mediated AmpC in Enterobacteriaceae isolated in a Brazilian Teaching Hospital BJM
Campana,Eloiza H.; Barbosa,Paula P.; Fehlberg,Lorena C.C.; Gales,Ana C..
In Brazil, the presence of plasmid-mediated AmpC (pAmpC)-producing isolates has been sporadically reported. We evaluated the frequency of pAmpC among 133 Enterobacteriaceae clinical isolates. The blaCMY-2-like gene was detected in a single Klebsiella pneumoniae isolate. In our study, the pAmpC frequency was very low as previously reported.
Tipo: Info:eu-repo/semantics/other Palavras-chave: Plasmids; Beta-lactamases; Beta-lactams; Brazil.
Ano: 2013 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822013000200023
Registros recuperados: 13
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