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Jacquot, Maude; Gonnet, Mathieu; Ferquel, Elisabeth; Abrial, David; Claude, Alexandre; Gasqui, Patrick; Choumet, Valerie; Charras-garrido, Myriam; Garnier, Martine; Faure, Benjamin; Sertour, Natacha; Dorr, Nelly; De Goer, Jocelyn; Vourc'H, Gwenael; Bailly, Xavier. |
Lyme borreliosis, one of the most frequently contracted zoonotic diseases in the Northern Hemisphere, is caused by bacteria belonging to different genetic groups within the Borrelia burgdorferi species complex, which are transmitted by ticks among various wildlife reservoirs, such as small mammals and birds. These features make the Borrelia burgdorferi species complex an attractive biological model that can be used to study the diversification and the epidemiology of endemic bacterial pathogens. We investigated the potential of population genomic approaches to study these processes. Sixty-three strains belonging to three species within the Borrelia burgdorferi complex were isolated from questing ticks in Alsace (France), a region where Lyme disease is... |
Tipo: Text |
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Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00667/77887/80052.pdf |
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Jacquot, Maude; Abrial, David; Gasqui, Patrick; Bord, Severine; Marsot, Maud; Masseglia, Sebastien; Pion, Angelique; Poux, Valerie; Zilliox, Laurence; Chapuis, Jean-louis; Vourc'H, Gwenael; Bailly, Xavier. |
Many pathogens are maintained by multiple host species and involve multiple strains with potentially different phenotypic characteristics. Disentangling transmission patterns in such systems is often challenging, yet investigating how different host species contribute to transmission is crucial to properly assess and manage disease risk. We aim to reveal transmission cycles of bacteria within the Borrelia burgdorferi species complex, which include Lyme disease agents. We characterized Borrelia genotypes found in 488 infected Ixodes ricinus nymphs collected in the Senart Forest located near Paris (France). These genotypes were compared to those observed in three sympatric species of small mammals and network analyses reveal four independent transmission... |
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Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00667/77885/80049.pdf |
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