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	Provedor de dados BJMBR (1) Autor Domenico,T. (1) Gonçalves,L.F. (1) Joelsons,G. (1) Manfro,R.C. (1) Palavra-chave Acute rejection (1) Diagnosis (1) Gene expression (1) Kidney transplantation (1) MRNA (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2018 (1) País Brazil (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Non-invasive messenger RNA transcriptional evaluation in human kidney allograft dysfunction BJMBR Joelsons,G.; Domenico,T.; Gonçalves,L.F.; Manfro,R.C.. The aim of the present study was to evaluate messenger RNA expression in kidney allograft recipients. Forty-four kidney transplant recipients were evaluated up to three months after grafting. After transplantation, peripheral blood samples were drawn sequentially for real-time polymerase chain reaction analyses of perforin and TIM-3 genes. Biopsies were obtained to evaluate acute graft dysfunction and interpreted according to the Banff classification. Eight patients presented episodes of acute rejection. Recipients with rejection had significantly higher levels of TIM-3 mRNA transcripts compared to those without rejection (median gene expression 191.2 and 36.9 mRNA relative units, respectively; P<0.0001). Also, perforin gene expression was higher in... Tipo: Info:eu-repo/semantics/article Palavras-chave: Kidney transplantation; Acute rejection; Gene expression; Diagnosis; MRNA. Ano: 2018 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018000700608 Registros recuperados: 1 Primeira ... 1 ... Última

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