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	Provedor de dados Acta Toxicol. Argent. (1) Autor Arocha-Piñango,Carmen L (1) Brazón,Josmary (1) Guerrero,Belsy (1) Sevcik, Carlos,Gina (1) Suze,D (1) Palavra-chave Coagulation (1) Factor Xa (1) Fibrinogen (1) Scorpion (1) Tipo do documento Info:eu-repo/semantics/article (1) Ano 2013 (1) País Argentina (1) Idioma Inglês (1)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 1 Primeira ... 1 ... Última Anticoagulant and factor Xa-like activities of Tityus discrepans scorpion venom Acta Toxicol. Argent. Brazón,Josmary; Guerrero,Belsy; Suze,D; Sevcik, Carlos,Gina; Arocha-Piñango,Carmen L. Tityus discrepans venom (TdV) produces a variety of haemostatic manifestations including alveoli fbrin deposition and/ or prothrombin and partial thromboplastin time (PT, PTT) alterations in mammals. In vitro studies have demonstrated that TdV contains tissue plasminogen activator-like (t-PA), fbrinolytic and plasmin inhibitory compounds and produces platelets activation through GPVI and a novel Src-dependent signalling pathway. The aim of this study is to describe the initial characterization of procoagulant and anticoagulant components from TdV. This venom was fractionated by exclusion molecular chromatography on a Sephadex G-50 column. The eluted material was collected as fve fractions called S1 to S5. These fractions and the whole venom were used to... Tipo: Info:eu-repo/semantics/article Palavras-chave: Scorpion; Coagulation; Fibrinogen; Factor Xa. Ano: 2013 URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851-37432013000100003 Registros recuperados: 1 Primeira ... 1 ... Última

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