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Polypropylene meshes coated with chitosan/polyethylene glycol for the reconstruction of the abdominal wall: an experimental study in rats Arq. Bras. Med. Vet. Zootec.
Rodrigues,D.F.; Mendes,F.F.; Melo,R.M.; Menezes,L.B.; Guimarães,L.L.B.; Silva,A.S.; Rammazzina Filho,W.A.; Moraes,A.M.; Paulo,N.M..
ABSTRACT The aim of this study was to characterize the tissue reactions triggered by the polypropylene mesh coated with chitosan and polyethylene glycol film, and if it’s able to prevent the formation of peritoneal adhesions. Defects in the abdominal wall of rats were induced and polypropylene meshes coated with chitosan/polyethylene glycol (CPEG group, n= 12) and uncoated (PP control group, n= 12) were implanted. On the fourth and forty-fifth postoperative day the formation of adhesion and the tissue reaction to the biomaterial was evaluated through histological and histochemical analysis. The area (P= 0.01) and severity (P= 0.002) of the adhesion was significatively less in the CPEG group. On the fourth day the foreign body reaction was less intense in...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Foreign-body reaction; Hernia; Peritoneal adhesions; Prosthesis; Surgical mesh.
Ano: 2019 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401198
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Histological evaluation and E-cadherin and β-catenin expression in kidney of dogs submitted to renal ischemia and reperfusion after chlorpromazine administration Arq. Bras. Med. Vet. Zootec.
Menezes,L.B.; Fioravanti,M.C.S.; Oliveira,F.A.; Silva,M.S.B.; Franco,L.G.; Sales,T.P.; Andrascko,M.M.; Guimarães,L.L.B.; Miguel,M.P.; Araújo,E.G..
ABSTRACT Renal ischemia can be associated with some urological procedures, such as renovascular surgery or kidney transplantation, that are often followed by acute renal failure. The aim of this study was to verify the E-cadherin and β-catenin localization in canine kidney in different times of renal ischemia and reperfusion after chlorpromazine application. Twelve dogs were randomly distributed equally into two groups. GroupA with ischemia and reperfusion without chlorpromazine and groupB with ischemia and reperfusion treated by chlorpromazine. GroupB received intravenous chlorpromazine, 15 min before the artery obstruction, which lasted 1 hour. After this period, the clamps in the renal arteries were released and the organ remained in reperfusion for 2...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Acute renal failure; Adherens junctions; Cell adhesion; Kidney tubular necrosis.
Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000501206
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