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Association of PPARγ2 polymorphisms with carcass and meat quality traits in a Pietrain x Jinhua F2 population Genet. Mol. Biol.
Chen,Zhe; Zhao,Xiaofeng; Jiang,Xiaoling; Guo,Xiaoling; Lv,Zunzhou; Zhou,Hongmei; Xu,Ningying.
The PPARγ2 gene is a key regulator of both proliferation and preadipocyte differentiation in mammals. Herein its genotype and allele frequencies were analyzed using PCR-SSCP in eight pig breeds (N = 416). Two kinds of polymorphisms of the PPARγ2 gene were detected, including a previously reported shift SNP A177G (Met59Val) in exon 1 and a novel silent mutation G876A in exon 5. The results revealed that European pig breeds carry a higher allele A frequency at the A177G locus and a fixed GG genotype at the G876A locus. Allele A at the G876A locus was only found in Jinhua pigs. The association between haplotype (A177G/G876A) and carcass and meat quality traits was analyzed in a Pietrain x Jinhua F2 population (N = 248). The PPARγ2 gene was found to be...
Tipo: Info:eu-repo/semantics/article Palavras-chave: PPARγ2 gene; Haplotype; Carcass and meat quality; Pigs.
Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572011000100011
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