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Sanches,R.F.; Crippa,J.A.S.; Hallak,J.E.C.; de Sousa,J.P.M.; Araújo,D.; Santos,A.C.; Zuardi,A.W.. |
The aim of the present study was to determine whether specific subgroups of schizophrenic patients, grouped according to electrodermal characteristics, show differences in the N-acetylaspartate/creatine plus choline (NAA / (Cr + Cho)) ratios in the frontal, cingulate and perirolandic cortices. Skin conductance levels (SCL) and skin conductance responses to auditory stimulation were measured in 38 patients with schizophrenia and in the same number of matched healthy volunteers (control). All subjects were submitted to multivoxel proton magnetic resonance spectroscopic imaging. When compared to the control group, patients presented significantly lower NAA / (Cr + Cho) ratios in the right dorsolateral prefrontal cortex (schizophrenia = 0.95 ± 0.03; control =... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Magnetic resonance spectroscopy; Skin conductance; Schizophrenia; N-acetylaspartate; Cingulate region; Dorsolateral prefrontal cortex. |
Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008001200015 |
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