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	Provedor de dados 56 (2) Autor He,J. (2) Ji,X.X. (1) Ling,H. (1) Liu,J. (1) Meng,Q. (1) Su,Q. (1) Tan,H. (1) Tang,Y.L. (1) Wang,B. (1) Wen,L. (1) Xia,H. (1) Zhai,S. (1) Zhou,J.G. (1) Zhu,Y. (1) Mais... Palavra-chave Aortic dissection (1) Cell cycle G2/M arrest (1) Checkpoint kinase-1 (1) Diallyl disulfide (1) Endovascular aortic repair (1) Gastric cancer (1) Open surgical repair (1) Type-B aortic dissection (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2016 (1) 2010 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide 56 Ling,H.; Wen,L.; Ji,X.X.; Tang,Y.L.; He,J.; Tan,H.; Xia,H.; Zhou,J.G.; Su,Q.. Diallyl disulfide (DADS) inhibits growth and induces cell cycle G2/M arrest in human gastric cancer MGC803 cells. In this study, 15 mg/L DADS exerted similar effects on growth and cell cycle arrest in human gastric cancer BGC823 cells. Due to the importance of cell cycle redistribution in DADS-mediated anti-carcinogenic effects, we investigated the role of checkpoint kinases (Chk1 and Chk2) during DADS-induced cell cycle arrest. We hypothesized that DADS could mediate G2/M phase arrest through either Chk1 or Chk2 signal transduction pathways. We demonstrated that DADS induced the accumulation of phosphorylated Chk1, but not of Chk2, and that DADS down-regulated Cdc25C and cyclin B1. The expression of mRNA and total protein for Chkl and Chk2 was unchanged.... Tipo: Info:eu-repo/semantics/article Palavras-chave: Diallyl disulfide; Cell cycle G2/M arrest; Checkpoint kinase-1; Gastric cancer. Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300008 Long-term efficacy of endovascular vs open surgical repair for complicated type-B aortic dissection: a single-center retrospective study and meta-analysis 56 Zhu,Y.; Wang,B.; Meng,Q.; Liu,J.; Zhai,S.; He,J.. This study aimed to evaluate the long-term survival and risk factors of traditional open surgical repair (OSR) vs thoracic endovascular aneurysm repair (TEVAR) for complicated type-B aortic dissection (TBAD). A total of 118 inpatients (45 OSR vs 73 TEVAR) with TBAD were enrolled from January 2004 to January 2015. Kaplan-Meier curves and Cox proportional hazards analysis were performed to identify the long-term survival rate and independent predictors of survival, respectively. Meta-analysis was used to further explore the long-term efficacy of OSR and TEVAR in the eight included studies using Review Manager 5.2 software. An overall 10-year survival rate of 41.9% was found, and it was similar in the two groups (56.7% OSR vs 26.1% TEVAR; log-rank P=0.953).... Tipo: Info:eu-repo/semantics/article Palavras-chave: Aortic dissection; Open surgical repair; Type-B aortic dissection; Endovascular aortic repair. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600707 Registros recuperados: 2 Primeira ... 1 ... Última

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