|
|
| Hughes, Kristelle; Ho, Raimana; Chazaud, Claire; Hermitte, Stéphanie; Greff, Stéphane; Butaud, Jean-françois; Filaire, Edith; Ranouille, Edwige; Berthon, Jean-yves; Raharivelomanana, Phila. |
| Fagraea berteroana is a tree used in traditional medicine in various islands of the South Pacific. Here, we studied its hair growth-inducing properties as suggested by one of its Marquesan ethno-uses in haircare. The ethyl acetate extract of the fruits of F. berteroana (FEAE) and four resulting fractions (FEAE-F0, FEAE-F1, FEAE-F2, and FEAE-F3) were tested on hair follicle dermal papilla cells to determine their cell proliferative activity. Furthermore, RT-qPCR analysis enabled gene modulation analysis, while immunostaining of the β-catenin protein was used to follow protein regulation. We found that the plant extracts induced a controlled, dose-dependent cell proliferation. FEAE-F0 simultaneously down-regulated Bone Morphogenetic Protein 2 (BMP2) mRNA... |
| Tipo: Text |
Palavras-chave: Fagraea berteroana; Hair growth; Ethnocosmetology; Marquesas islands; Gentianaceae. |
| Ano: 2021 |
URL: https://archimer.ifremer.fr/doc/00678/79021/81426.pdf |
| |
