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| Hernández-Salinas,Romina; Decap,Valerie; Leguina,Alberto; Cáceres,Patricio; Perez,Druso; Urquiaga,Ines; Iturriaga,Rodrigo; Velarde,Victoria. |
| BACKGROUND: Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrease oxidative stress in rats fed with a high fructose diet. METHODS: Male Sprague-Dawley rats weighing 180 g were divided into four groups according to their feeding protocols. Rats were fed with control diet (C), control plus 20 % WGP (C + WGP), 50 % high fructose (HF) or 50 % fructose plus 20 % WGP (HF + WGP) for 16 weeks. Blood glucose, insulin and triglycerides, weight, and arterial blood pressure were measured. Homeostasis model assessment (HOMA) index... |
| Tipo: Journal article |
Palavras-chave: Insulin resistance; Oxidative stress; Metabolic syndrome; Wine grape powder. |
| Ano: 2015 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100053 |
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