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Groisillier, Agnes; Herve, Christiane; Jeudy, Alexandra; Rebuffet, Etienne; Pluchon, Pierre Francois; Chevolot, Yann; Flament, Didier; Geslin, Claire; Morgado, Isabel M.; Power, Deborah; Branno, Margherita; Moreau, Herve; Michel, Gurvan; Boyen, Catherine; Czjzek, Mirjam. |
Background: The production of stable and soluble proteins is one of the most important steps prior to structural and functional studies of biological importance. We investigated the parallel production in a medium throughput strategy of genes coding for proteins from various marine organisms, using protocols that involved recombinatorial cloning, protein expression screening and batch purification. This strategy was applied in order to respond to the need for post-genomic validation of the recent success of a large number of marine genomic projects. Indeed, the upcoming challenge is to go beyond the bioinformatic data, since the bias introduced through the genomes of the so called model organisms leads to numerous proteins of unknown function in the still... |
Tipo: Text |
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Ano: 2010 |
URL: http://archimer.ifremer.fr/doc/00011/12219/9003.pdf |
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Berthome, Jean-paul; Herve, Christiane. |
Quality assurance specifications, standards and inspection organisms are presented. French and international status shows that quality assurance is sharply expanding. Several french research institutes have started this kind of step wich has led to analysis laboratories accreditation. European regulation will oblige organisms such as IFREMER to give anal ysis results coming from accreditated laboratories (thermotolerant coliforms and phycotoxins). Different phases of laboratories accreditation are presented. Reflection on quality assurance in research has been developed on the behalf of Upper Education and Research Ministry. |
Tipo: Text |
Palavras-chave: Assurance qualité; Accréditation; Quality assurance; Accreditation. |
Ano: 1996 |
URL: http://archimer.ifremer.fr/doc/00408/51924/52547.pdf |
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