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Clinical and pathological challenges in the diagnosis of late-onset biliary atresia: four case studies 56
Fontenele,J.P.U.; Schenka,A.A.; Hessel,G.; Jarry,V.M.; Escanhoela,C.A.F..
Biliary atresia (BA) is classically described at the neonatal age. However, rare cases of BA in older infants have also been reported. We report four cases of late-onset BA in infants older than 4 weeks (3 males, 1 female), and describe the diagnostic and management difficulties. One of the cases had a late-onset (29 weeks) presentation with a successful surgical procedure. We highlight the importance of this unusual differential diagnosis in infants with cholestatic syndrome, who may benefit from Kasai surgery, regardless of age.
Tipo: Info:eu-repo/semantics/report Palavras-chave: Kasai operation; Cholestatic syndrome; Infants.
Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000300501
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Gastric emptying in rats with acetaminophen-induced hepatitis 56
Hessel,G.; Collares,E.F..
The objective of this work was to study the gastric emptying (GE) of liquids in fasted and sucrose-fed rats with toxic hepatitis induced by acetaminophen. The GE of three test meals (saline, glucose and mayonnaise) was evaluated in Wistar rats. For each meal, the animals were divided into two groups (N = 24 each). Group I was fed a sucrose diet throughout the experiment (66 h) while group II was fasted. Forty-two hours after the start of the experiment, each group was divided into two subgroups (N = 12 each). Subgroup A received a placebo and subgroup B was given acetaminophen (1 g/kg). Twenty-four hours later, the GE of the three test meals was assessed and blood samples were collected to measure the serum levels of alanine aminotransferase (ALT),...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Gastric emptying; Acetaminophen; Experimental hepatitis.
Ano: 1998 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1998000900006
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