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Whole genome de novo sequencing of common quail and grey partridge Organic Eprints
Holm, Lars-Erik; Panitz, Frank; Bendixen, Christian; Talbot , R.; Smith, S.; Andersen, Liselotte Wesley; Burt, D..
The development of next-generation sequencing technologies enables rapid generation of large amounts of genome sequences. Next-generation sequencing was utilised to perform whole genome sequencing of two Phasianidae, common quail (Coturnix coturnix) and grey partridge (Perdix perdix). Sequence data corresponding to 8 to 9 fold coverage of the genomes of the two species were obtained. The amount of sequence data enabled generation of a rough de novo genome assembly suitable for either the identification of the sequence of specific genes or for use in comparative studies with other birds, such as chicken and turkey. Likewise, it was possible to identify numerous SNPs and microsatellites for use in other studies.
Tipo: Journal paper Palavras-chave: "Organics" in general.
Ano: 2013 URL: http://orgprints.org/23313/7/23313.pdf
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Whole genome de novo sequencing of quail and grey partridge Organic Eprints
Holm, Lars-Erik; Panitz, Frank; Burt, D.; Talbot , R.; Smith, S.; Andersen, Liselotte Wesley; Bendixen, Christian.
Sufficient sequence data to initiate genome sequencing of quail and grey partridge has been obtained. The difference in assembly quality between species is a consequence of the difference in length of the sequence reads (54 cycles versus 101 cycles). Additional data will be required before sequence assembly are being performed. Specifically longer sequence reads (especially in quail) will be necessary to generate assemblies of a reasonable quality.
Tipo: Conference paper, poster, etc. Palavras-chave: "Organics" in general.
Ano: 2011 URL: http://orgprints.org/19057/4/19057.pdf
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Landscape population genetics and the role of organic farming Organic Eprints
Marchi, Chiara; Andersen, Liselotte Wesley; Holm, Lars-Erik; Loeschcke, Volker.
This project aims at understanding the effect of different farming systems on the genetic diversity of common agricultural species. It is well known that organic farming generally improves the biodiversity and abundance of species in the agricultural landscape (Hole et al., 2005). A reduction in species number and abundance has been shown as a result of the intensification of farming suggesting a relationship between farming intensity and species abundance (e.g. Stoate et al., 2001). Anyway, none of the studies that investigated the effects of pesticides presence and farming intensity has investigated the effect on the genetic diversity and isolation of the populations. It has been shown that, despite the theoretical expectations, also very abundant...
Tipo: Conference paper, poster, etc. Palavras-chave: "Organics" in general.
Ano: 2009 URL: http://orgprints.org/16304/1/16304.pdf
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Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals Organic Eprints
Bouwman, Aniek C.; Daetwyler, Hans D.; Chamberlain, Amanda J.; Hurtado Ponce, Carla; Sargolzaei, Mehdi; Schenkel, Flavio S.; Sahana, Goutam; Govignon-Gion, Armelle; Boitard, Simon; Dolezal, Marlies; Pausch, Hubert; Brøndum, Rasmus F.; Bowman, Phil J.; Thomsen, Bo; Guldbrandtsen, Bernt; Lund, Morgns S.; Servin, Bertrand; Garrick, Dorian J.; Reecy, James; Vilkki, Johanna; Bagnato, Alessandro; Wang, Min; Hoff, Jesse L.; Schnabel, Robert D.; Taylor, Jeremy F.; Vinkhuyzen, Anna A. E.; Panitz, Frank; Bendixen, Christian; Holm, Lars-Erik; Gredler, Birgit; Hozé, Chris; Boussaha, Mekki; Sanchez, Marie-Pierre; Rocha, Dominique; Capitan, Aurelien; Tribout, Thierry; Barbat, Anne; Croiseau, Pascal; Drögemüller, Cord; Jagannathan, Vidhya; Vander Jagt, Christy; Bieber, Anna; Purfield, Deidre C.; Berry, Donagh P.; Emmerling, Reiner; Götz, Kay-Uwe; Frischknecht, Mirjam; Russ, Ingolf; Sölkner, Johann; Van Tassel, Curtis P.; Fries, Ruedi; Stothard, Paul; Veerkamp, Roel F.; Boichard, Didier; Goddard, Mike E.; Hayes, Ben J..
Stature is affected by many polymorphisms of small effect in humans1. In contrast, variation in dogs, even within breeds, has been suggested to be largely due to variants in a small number of genes2,3. Here we use data from cattle to compare the genetic architecture of stature to those in humans and dogs. We conducted a meta-analysis for stature using 58,265 cattle from 17 populations with 25.4 million imputed whole-genome sequence variants. Results showed that the genetic architecture of stature in cattle is similar to that in humans, as the lead variants in 163 significantly associated genomic regions (P < 5 × 10−8) explained at most 13.8% of the phenotypic variance. Most of these variants were noncoding, including variants that were also expression...
Tipo: Journal paper Palavras-chave: Dairy cattle; Beef cattle; Breeding and genetics.
Ano: 2018 URL: http://orgprints.org/35102/1/Bouwman-etal-2018-NatureGenetics-Vol50-p362-367.pdf
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Whole genome de novo sequencing of quail and grey partridge Organic Eprints
Holm, Lars-Erik; Panitz, Frank; Burt, D.; Talbot , R.; Smith, S.; Andersen, Liselotte Wesley; Bendixen, Christian.
Sufficient sequence data to initiate genome sequencing of quail and grey partridge has been obtained. The difference in assembly quality between species is a consequence of the difference in length of the sequence reads (54 cycles versus 101 cycles). Additional data will be required before sequence assembly are being performed. Specifically longer sequence reads (especially in quail) will be necessary to generate assemblies of a reasonable quality.
Tipo: Conference paper, poster, etc. Palavras-chave: "Organics" in general; Biodiversity and ecosystem services.
Ano: 2011 URL: http://orgprints.org/19314/7/19314.pdf
Registros recuperados: 5
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