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| Porfirio,Zenaldo; Ribeiro,Micheline P.; Estevam,Cicero S.; Houly,Ricardo L. S.; Sant'Ana,Antonio Euzébio G.. |
| Cyanobacteria (Microcystis aeruginosa), which produce powerful hepatotoxic cyclopeptides, were collected and submitted to the determination of toxicity through intraperitoneal injections made in 30 and 90 days-old Swiss albino mice. The liver and the spleen were histopathologically analyzed and the weight and vital signs development were monitored. Test of toxicity resulted in a LD50 of 154.28 mg.Kg-1. M. aeruginosa represented 95% of the analyzed biomass. The ratios between liver weight and body weight in the animal inoculated with a single dose were 6.0% and 7.2%, with multi doses 7.0% and 7.5% and in the control animals 4.0% and 5.0%, for adult and young animals, respectively. There was an accentuated increase in the volume and weight of the spleen, and... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Microcystis aeruginosa; Cyanobacteria; Hepatomegaly; Splenomegaly. |
| Ano: 1999 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37141999000300016 |
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