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	Provedor de dados 56 (2) Autor Huang,X. (2) Bechlars,S. (1) Kremsner,P.G. (1) Kun,J.F.J. (1) Ma,J. (1) Teng,Y. (1) Velavan,T.P. (1) Yang,H. (1) Mais... Palavra-chave Apoptosis (1) Invasion (1) MiR-9 (1) NF-κB (1) Ovarian cancer (1) Polymorphism (1) Propofol (1) Regulatory T cells (1) Transfection (1) Tumor necrosis factor receptor superfamily (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Info:eu-repo/semantics/other (1) Ano 2016 (1) 2011 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Propofol inhibits invasion and growth of ovarian cancer cells via regulating miR-9/NF-κB signal 56 Huang,X.; Teng,Y.; Yang,H.; Ma,J.. Propofol is one of the most commonly used intravenous anesthetic agents during cancer resection surgery. A previous study has found that propofol can inhibit invasion and induce apoptosis of ovarian cancer cells. However, the underlying mechanisms are not known. miR-9 has been reported to be little expressed in ovarian cancer cells, which has been related to a poor prognosis in patients with ovarian cancer. Studies have also demonstrated that propofol could induce microRNAs expression and suppress NF-κB activation in some situations. In the present study, we assessed whether propofol inhibits invasion and induces apoptosis of ovarian cancer cells by miR-9/NF-κB signaling. Ovarian cancer ES-2 cells were transfected with anti-miR-9 or p65 cDNA or p65 siRNA... Tipo: Info:eu-repo/semantics/article Palavras-chave: Propofol; Ovarian cancer; MiR-9; NF-κB; Apoptosis; Invasion. Ano: 2016 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016001200605 Novel regulatory SNPs in the promoter region of the TNFRSF18 gene in a Gabonese population 56 Velavan,T.P.; Bechlars,S.; Huang,X.; Kremsner,P.G.; Kun,J.F.J.. Parasites are accountable for driving diversity within immune gene families. We identified and investigated regulatory single nucleotide polymorphisms (SNPs) in the promoter regions of the tumor necrosis factor receptor superfamily member 18 (TNFRSF18) gene by direct sequencing in a group of male Gabonese individuals exposed to a wide array of parasitic diseases such as malaria, filariasis and schistosomiasis. Two new promoter variants were identified in 40 individuals. Both novel variants were heterozygous and were linked to SNP #rs3753344 (C/T), which has been described. One of the SNP variants (ss2080581728) was close to the general transcription factor site, the TATA box. We further validated these new promoter variants for their allelic gene... Tipo: Info:eu-repo/semantics/other Palavras-chave: Tumor necrosis factor receptor superfamily; Polymorphism; Transfection; Regulatory T cells. Ano: 2011 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000500006 Registros recuperados: 2 Primeira ... 1 ... Última

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